ArticleStatistics in medicine2022
A modified self-controlled case series method for event-dependent exposures and high event-related mortality, with application to COVID-19 vaccine safety.
Article in Statistics in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 58 citations in OpenAlex.
- Cardiac Adverse Events and Remdesivir in Hospitalized Patients With COVID-19: A Post Hoc Safety Analysis of the Randomized DisCoVeRy Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Trial
- Contrast-Associated AKI in Hospitalized Adults With Sickle Cell Disease.Kidney international reports · 2026Article
- Oral antibiotic exposure and urinary tract infection risk in adults: a self-controlled case series study.EClinicalMedicine · 2026Article
- Delayed Exposures and Pre-Exposure Periods in Self-Controlled Case Series Studies.Statistics in medicine · 2026Article
- COVID-19 vaccination and short-term mortality risk: a nationwide self-controlled case series study in The Netherlands.European journal of epidemiology · 2026Article
- COVID-19 mRNA Vaccination and 4-Year All-Cause Mortality Among Adults Aged 18 to 59 Years in France.JAMA network open · 2025Article
- Risk of Ischaemic Stroke Varies With Antithrombotic Drugs Use in Proton Pump Inhibitor Users: A Self-Controlled Case Series Study.Pharmacoepidemiology and drug safety · 2025Article
- Opioid Use After Hip Fracture and Subsequent Fracture Outcomes: A Self-Controlled Case Series Design.Pharmacoepidemiology and drug safety · 2025Article
- Short-Term Risk of Cardiovascular Events in People Newly Diagnosed With Gout.Arthritis & rheumatology (Hoboken, N.J.) · 2025Article
- Core Concepts: Self-Controlled Designs in Pharmacoepidemiology.Pharmacoepidemiology and drug safety · 2025Review
- Acute Appendicitis After COVID-19 Vaccines in Italy: A Self-Controlled Case Series Study.Drug safety · 2024Article
- Risk of Cardiovascular Events After Influenza: A Population-Based Self-Controlled Case Series Study, Spain, 2011-2018.The Journal of infectious diseases · 2024Article
- Ischemic Stroke After Bivalent COVID-19 Vaccination: Self-Controlled Case Series Study.JMIR public health and surveillance · 2024Article
- Unveiling unique clinical phenotypes of hip fracture patients and the temporal association with cardiovascular events.Nature communications · 2024Article
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- Effectiveness and Respiratory Adverse Events Following Inactivated and mRNA COVID-19 Vaccines in Patients with COPD and Asthma: A Chinese Population-Based Study.Drug safety · 2024Article
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- Nationwide safety surveillance of COVID-19 mRNA vaccines following primary series and first booster vaccination in Singapore.Vaccine: X · 2023Article
- Risk of Guillain-Barré Syndrome Following COVID-19 Vaccines: A Nationwide Self-Controlled Case Series Study.Neurology · 2023Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We propose a modified self-controlled case series (SCCS) method to handle both event-dependent exposures and high event-related mortality. This development is motivated by an epidemiological study undertaken in France to quantify potential risks of cardiovascular events associated with COVID-19 vaccines. Event-dependence of vaccinations, and high event-related mortality, are likely to arise in other SCCS studies of COVID-19 vaccine safety. Using this case study and simulations to broaden its scope, we explore these features and the biases they may generate, implement the modified SCCS model, illustrate some of the properties of this model, and develop a new test for presence of a dose effect. The model we propose has wider application, notably when the event of interest is death.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.