ArticleResearch on child and adolescent psychopathology2022
Developmental Cascade Effects of Maternal Depression on Offspring Substance Use Across Adolescence: Pathway Through Mother-Child Relationship Quality and Peer Deviancy.
Article in Research on child and adolescent psychopathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Socioeconomic factors and sex effects of postpartum maternal depression on offspring internalizing symptoms: a systematic review and meta-analysis.BMC medicine · 2025Pooled it
- Effectiveness of cognitive behavioural therapy-based interventions for maternal perinatal depression: a systematic review and meta-analysis.BMC psychiatry · 2023Pooled it
- Teacher-student relationships and adult outcomes: Developmental cascades via childhood executive function and behavioral dysregulation.Child development · 2026Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
There is evidence that maternal depression can disrupt adolescent social development and trigger a risk cascade to adolescent substance use that involves poor quality mother-child relationships (Lovejoy et al., 2000) and affiliation with deviant peers (Visser et al., 2012). However, relatively little work has considered maternal depression as a catalyst for this risk pathway to adolescent substance use. The current study aims to clarify whether maternal depression has cascading effects to adolescent substance use through related developmental systems. Using structural equation modeling and bootstrapping for testing indirect effects, we tested the prospective association between maternal depression and middle adolescent substance use and whether poor mother-child relationship quality and peer deviancy mediated this relationship. We controlled for a variety of important cofounding variables. The sample included N = 338 adolescents (57% female; predominantly non-Hispanic Caucasian (83.14%) or African American (8.88%)) and mothers drawn from a larger nine-year longitudinal study of adolescent substance use. Data from wave 1 through wave 6 of the longitudinal project were utilized. The average age of adolescents was 11.6, 12.6, 13.6, 14.6, 15.5, and 16.6 at W1-W6, respectively. The indirect effect from maternal depression to substance use was supported (ab = 0.03, 95% CI [0.002, 0.07]). Findings emphasize that future work should more closely examine how maternal depression operates in developmental cascade models of adolescent substance use.
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Registered trials
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