Evidence map›Paper›PMID 35091835›Full record

ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2022

Human pluripotent stem cell-derived functional sympathetic neurons express ACE2 and RAAS components: a framework for studying the effect of COVID-19 on sympathetic responsiveness.

Hsueh-Fu Wu, Chia-Wei Huang, Kanupriya R Daga, Ross A Marklein, Natalia Ivanova, Nadja Zeltner

Open access · bronzeAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hsueh-Fu WuCenter for Molecular Medicine, University of Georgia, 325 Riverbend Road, Athens, GA, 30602, USA.
Chia-Wei HuangDepartment of Biochemistry and Molecular Biology, Franklin College of Arts and Sciences, University of Georgia, Athens, GA, USA.
Kanupriya R DagaSchool of Chemical, Materials and Biomedical Engineering, University of Georgia, Athens, GA, USA.
Ross A MarkleinSchool of Chemical, Materials and Biomedical Engineering, University of Georgia, Athens, GA, USA.
Natalia IvanovaCenter for Molecular Medicine, University of Georgia, 325 Riverbend Road, Athens, GA, 30602, USA.
Nadja ZeltnerCenter for Molecular Medicine, University of Georgia, 325 Riverbend Road, Athens, GA, 30602, USA. nadja.zeltner@uga.edu.ORCID 0000-0002-2978-2507
University of Georgia · US

Funding

Precision Medicine for the Peripheral Nervous System Disorder Familiar DysautonomiaR01NS114567 · NINDS · UNIVERSITY OF GEORGIA · PI Nadja Zeltner · 2021 to 2026
$3.0M
NINDS NIH HHS 1R01NS114567-01A1NINDS NIH HHS R01 NS114567
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Angiotensin-Converting Enzyme 2COVID-19NeuronsPluripotent Stem CellsHumansRenin-Angiotensin SystemSARS-CoV-2Angiotensin-Converting Enzyme 2

Identifiers

PMID35091835
PMCPMC8799422
OpenAlexW4210722667

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.