ArticleEuropean archives of psychiatry and clinical neuroscience2022
Impaired delay discounting and time sensitivity in methcathinone use disorder.
Article in European archives of psychiatry and clinical neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Modulation of dlPFC function and decision-making capacity by repetitive transcranial magnetic stimulation in methamphetamine use disorder.Translational psychiatry · 2024Article
- Effects of Prenatal Methcathinone Exposure on the Neurological Behavior of Adult Offspring.Current neuropharmacology · 2024Article
- Patients with episodic migraine without aura have an increased rate of delayed discounting.Brain and behavior · 2024Article
- Gender difference in network relationship between inter-temporal decisions and prefrontal activation levels in internet gaming disorder.Psychoradiology · 2023Article
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Authors and funding
11 authors at 6 institutions in 2 countries.
Funding
Abstract
Substance use disorder (SUD) is characterized by continued drug use despite adverse consequences. Methcathinone is a new type of psychoactive substance that is associated with high excitement and impulsive behaviors. However, it is unclear if individuals with methcathinone use disorders (MCUD) are with impaired decision-making ability. We analyzed the task performance in 45 male MCUD subjects and 35 male matched healthy controls (HC) with intertemporal decision-making task. Constant sensitivity discounting model was used to estimate potential changes in both discounting rate and time sensitivity. The results showed that MCUD individuals exhibited a higher delay discounting rate (p = 0.003, Cohen's d = 0.683) and reduced sensitivity to time (p < 0.001, Cohen's d = 1.662). The delay discounting rate was correlated to the first age for drug use (r = - 0.41, p = 0.004), and the time sensitivity was negatively correlated with the duration of abstinence (r = - 0.31, p = 0.036). We conclude that MCUD individuals are with impaired decision-making ability and time perception disturbances.
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