ArticleScientific reports2022
Physiological responses of Holstein calves to heat stress and dietary supplementation with a postbiotic from Aspergillus oryzae.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 32 citations in OpenAlex.
- Targeting the human gut microbiome: a comparative review of probiotics, prebiotics, synbiotics, and postbiotics.Journal of advanced research · 2026Review
- Gut Microbiome Dysbiosis in Metabolic Syndrome: Current Evidence and Emerging Perspectives.Nutrients · 2026Review
- Resveratrol supplementation improved antioxidant capacity and mitigated the impact of heat stress in lactating dairy cows.JDS communications · 2026Article
- Yeast-Derived Postbiotics for Prevention of Enteric Diseases in Farm Animals: Current Insights and Future Perspectives.Veterinary sciences · 2026Review
- Effects of Sodium Butyrate and Organic Zinc Supplementation on Performance, Mineral Metabolism, and Intestinal Health of Dairy Calves.Animals : an open access journal from MDPI · 2026Article
- Research progress on the mechanisms and intervention strategies of microbiota-gut-brain axis dysfunction under heat stress.Frontiers in physiology · 2026Review
- Transcriptome changes in leukocytes of dairy calves exposed to heat stress.Translational animal science · 2026Article
- Postbiotics: Multifunctional Microbial Products Transforming Animal Health and Performance.Veterinary sciences · 2025Review
- Postbiotics: an insightful review of the latest category in functional biotics.World journal of microbiology & biotechnology · 2025Review
- Physiological responses and reproductive performance of naturally heat-stressed rabbit does treated with postbiotic of Bacillus subtilis and Saccharomyces cerevisiae in free and nano-encapsulated forms.BMC veterinary research · 2025Article
- Optimizing Cost-Effective gene expression phenotyping approaches in cattle using 3' mRNA sequencing.BMC genomics · 2025Article
- Climate-smart livestock nutrition in semi-arid Southern African agricultural systems.Frontiers in veterinary science · 2025Review
- Skin transcriptomic analysis reveals candidate genes and pathways associated with thermotolerance in hair sheep.International journal of biometeorology · 2024Article
- The postbiotic potential ofFrontiers in microbiology · 2024Review
- The ameliorative effect of bergamot oil nano-emulsion in stressed rabbit bucks: Influence on blood biochemical parameters, redox status, immunity indices, inflammation markers, semen quality, testicular changes and the expression of HSPs genes.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023Article
- Dietary Fermentation Product ofAnimals : an open access journal from MDPI · 2023Article
- Frequently asked questions about the ISAPP postbiotic definition.Frontiers in microbiology · 2023Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increased ambient temperature causes heat stress in mammals, which affects physiological and molecular functions. We have recently reported that the dietary administration of a postbiotic from Aspergillus oryzae (AO) improves tolerance to heat stress in fruit flies and cattle. Furthermore, heat-induced gut dysfunction and systemic inflammation have been ameliorated in part by nutritional interventions. The objective of this study was to characterize the phenotypic response of growing calves to heat stress compared to thermoneutral ad libitum fed and thermoneutral feed-restricted counterparts and examining the physiologic alterations associated with the administration of the AO postbiotic to heat-stressed calves with emphasis on intestinal permeability. In this report, we expand previous work by first demonstrating that heat stress reduced partial energetic efficiency of growth in control (45%) but not in AO-fed calves (62%) compared to thermoneutral animals (66%). While heat stress increased 20% the permeability of the intestine, AO postbiotic and thermoneutral treatments did not affect this variable. In addition, AO postbiotic reduced fecal water content relative to thermoneutral and heat stress treatments. Heat stress increased plasma concentrations of serum amyloid A, haptoglobin and lipocalin-2, and administration of AO postbiotic did not ameliorate this effect. In summary, our findings indicated that heat stress led to reduced nutrient-use efficiency and increased systemic inflammation. Results suggest that the AO postbiotic improved energy-use efficiency, water absorption, and the intestinal permeability in heat stress-mediated increase in gut permeability but did not reduce heat stress-mediated rise in markers of systemic inflammation.
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