Evidence map›Paper›PMID 35091663›Full record

ArticleScientific reports2022

Contribution of obesity and cardiometabolic risk factors in developing cardiovascular disease: a population-based cohort study.

Mahmood Bakhtiyari, Elham Kazemian, Kourosh Kabir, Farzad Hadaegh, Sepehr Aghajanian, Parham Mardi, Nooshin Taherzadeh Ghahfarokhi, Ali Ghanbari, Mohammad Ali Mansournia, Freidoun Azizi

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Elevated HbA1c is associated with advanced brain age in severe obesity.medRxiv : the preprint server for health sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mahmood BakhtiyariNon-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran.
Elham KazemianPrevention of Metabolic Disorders Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Kourosh KabirDepartment of Community Medicine, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Farzad HadaeghPrevention of Metabolic Disorders Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. farzad.hadaegh@gmail.com.
Sepehr AghajanianStudent Research Committee, Alborz University of Medical Sciences, Karaj, Iran.
Parham MardiStudent Research Committee, Alborz University of Medical Sciences, Karaj, Iran.
Nooshin Taherzadeh GhahfarokhiStudent Research Committee, Alborz University of Medical Sciences, Karaj, Iran.
Ali GhanbariDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Pour-Sina Street, Tehran, Iran.
Mohammad Ali MansourniaDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Pour-Sina Street, Tehran, Iran. mansournia_ma@yahoo.com.
Freidoun AziziEndocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to assess the effects of central and general adiposity on development of cardiovascular diseases (CVDs) mediated by cardiometabolic risk factors and to analyze their degree of dependency for mediating their effects. To this end, data from the the Tehran Lipid and Glucose Study cohort with 6280 participants were included in this study. The hazard ratios were calculated using a 2-stage regression model in the context of a survival model. Systolic blood pressure (BP), total serum cholesterol, and fasting plasma glucose were designated as mediators. Assessing the interactions revealed that BP was the most important mediator for general ( (HR

Indexed as

Cardiometabolic Risk FactorsCardiovascular DiseasesObesityAdultAgedBlood GlucoseBlood PressureBody Mass IndexCohort StudiesFemaleHumansIranMaleMiddle AgedObesity, AbdominalRisk FactorsBlood Glucose

Identifiers

PMID35091663
PMCPMC8799723

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.