ArticleProceedings of the National Academy of Sciences of the United States of America2022
Open access · greenAbstract read
In one paragraph
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
10.1field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 50 citations in OpenAlex.
- Using the simple telegraph model to decipher transcriptional burst regulation across genome-wide data.iScience · 2026Article
- PANoptosis and Immune Remodeling in the Tumor Microenvironment.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Review
- Heterogeneous nuclear ribonucleoprotein K in cancer biology and its therapeutic applications (Review).Molecular medicine reports · 2026Review
- Targeting LAPTM5 enhances AML sensitivity to cytarabine through autophagy inhibition.Cell death & disease · 2026Article
- Role of ASLNC168501 in regulating hair follicle stem cell activity via the AR/miR-128-3p/IGF-1 pathway.Stem cell research & therapy · 2026Article
- Integrated WGCNA of lncRNA-mRNA Networks Identifies Novel Hub Genes and Potential Therapeutic Agents for Liver Cirrhosis via Molecular Docking Validation.International journal of molecular sciences · 2026Article
- Lysosome-dependent cell death in hepatocellular carcinoma: unlocking the therapeutic potential of natural products.Frontiers in pharmacology · 2026Review
- A small-molecule anti-cancer drug for long-acting lysosomal damage.Acta pharmaceutica Sinica. B · 2025Article
- P4HA2 interacted with ATAD3A to modulate PINK1/parkin-dependent mitophagy andCell death & disease · 2025Article
- LAMP2-FLOT2 interaction enhances autophagosome-lysosome fusion to protect the septic heart in response to ILC2.Autophagy · 2025Article
- The EGR1-mediated lncRNA TENM3-AS1 potentiates gastric cancer metastasis via reprogramming fatty acid metabolism.Molecular cancer · 2025Article
- Lysosomes: guardians and healers within cells- multifaceted perspective and outlook from injury repair to disease treatment.Cancer cell international · 2025Review
- Long non-coding RNAs in humans: Classification, genomic organization and function.Non-coding RNA research · 2025Review
- Role of non-coding RNA through nanomedicine: the novel therapeutic and diagnostic approaches.BioImpacts : BI · 2025Review
- Bioinformatic analyses reveal lysosomal-associated protein transmembrane 5 as a potential therapeutic target in lipotoxicity-induced injury in diabetic kidney disease.Renal failure · 2024Article
- Lysosomal transmembrane protein 5: Impact on immune cell function and implications for immune-related deficiencies.Heliyon · 2024Review
- Prosapogenin A induces GSDME-dependent pyroptosis of anaplastic thyroid cancer through vacuolar ATPase activation-mediated lysosomal over-acidification.Cell death & disease · 2024Article
- DRAIC mediates hnRNPA2B1 stability and mOncogene · 2024Article
- Therapeutic strategies of targeting non-apoptotic regulated cell death (RCD) with small-molecule compounds in cancer.Acta pharmaceutica Sinica. B · 2024Review
- ZKSCAN5 activates LAPTM5 expression by recruiting SETD7 to promote metastasis in pancreatic ductal adenocarcinoma.Histology and histopathology · 2024Article
Corrections and comments
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Authors and funding
24 authors at 7 institutions in 1 country.
Xiwang YangMedical School of Guizhou University, Guiyang 550025, China.ORCID 0000-0002-9242-6222
Ya WenMedical School of Guizhou University, Guiyang 550025, China.ORCID 0000-0001-8621-8016
Shaomin LiuGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.
Liqiang DuanShanxi Academy of Advanced Research and Innovation, Taiyuan 030032, China.
Tongfeng LiuMedical School of Guizhou University, Guiyang 550025, China.
Zhou TongShanxi Academy of Advanced Research and Innovation, Taiyuan 030032, China.ORCID 0000-0002-9867-2838
Zhuo WangShanxi Academy of Advanced Research and Innovation, Taiyuan 030032, China.
Yinmin GuCAS Key Laboratory of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.
Yibo XiShanxi Academy of Advanced Research and Innovation, Taiyuan 030032, China.
Xiaodong WangCAS Key Laboratory of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.
Dingsan LuoCAS Key Laboratory of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.ORCID 0000-0001-7379-1876
Ruobing ZhangCAS Key Laboratory of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.
Yajuan LiuShanxi Academy of Advanced Research and Innovation, Taiyuan 030032, China.
Yang WangShanxi Academy of Advanced Research and Innovation, Taiyuan 030032, China.
Tianyou ChengShanxi Academy of Advanced Research and Innovation, Taiyuan 030032, China.ORCID 0000-0002-7012-520X
Siyuan JiangCAS Key Laboratory of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.
Xiaofeng ZhuMedical School of Guizhou University, Guiyang 550025, China.
Xiaohui YangCAS Key Laboratory of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.ORCID 0000-0001-5175-5209
Yongbo PanShanxi Academy of Advanced Research and Innovation, Taiyuan 030032, China.
Shuwen ChengCancer Center, Taikang Xianlin Drum Tower Hospital, Nanjing University School of Medicine, Nanjing 210046, China.
Qinong YeDepartment of Medical Molecular Biology, Beijing Institute of Biotechnology, Collaborative Innovation Center for Cancer Medicine, Beijing 100850, China.
Jinfei ChenDepartment of Oncology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China; jinfeichen@sohu.com xuxiaod5@mail.sysu.edu.cn gaos@sibet.ac.cn.ORCID 0000-0001-5874-3462
Xiaoding XuGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China; jinfeichen@sohu.com xuxiaod5@mail.sysu.edu.cn gaos@sibet.ac.cn.ORCID 0000-0002-9785-6731
Shan GaoCAS Key Laboratory of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China; jinfeichen@sohu.com xuxiaod5@mail.sysu.edu.cn gaos@sibet.ac.cn.
Shanxi Academy of Building Research · CNChinese Academy of Sciences · CNGuizhou University · CNSun Yat-sen University · CNNanjing Drum Tower Hospital · CNPeking University · CNWenzhou Medical University · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lysosome plays important roles in cellular homeostasis, and its dysregulation contributes to tumor growth and survival. However, the understanding of regulation and the underlying mechanism of lysosome in cancer survival is incomplete. Here, we reveal a role for a histone acetylation-regulated long noncoding RNA termed
Indexed as
ApoptosisCell DeathCell Line, TumorCell SurvivalChinaGene ExpressionGene Expression Regulation, NeoplasticHeterogeneous-Nuclear Ribonucleoprotein KHumansIntracellular MembranesLysosomesMembrane ProteinsNeoplasmsRNA, Long NoncodingHeterogeneous-Nuclear Ribonucleoprotein KHNRNPK protein, humanLAPTM5 protein, humanMembrane ProteinsRNA, Long NoncodingapoptosishnRNP KLAPTM5LCDRlysosome
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.