Evidence map›Paper›PMID 35091438›Full record

ArticleThe British journal of ophthalmology2023

Reproducibility of deep learning based scleral spur localisation and anterior chamber angle measurements from anterior segment optical coherence tomography images.

Peng Liu, Risa Higashita, Philip Yawen Guo, Keiichiro Okamoto, Fei Li, Anwell Nguyen, Rei Sakata, Lixin Duan, Makoto Aihara, Shan Lin and 3 more

Abstract readMulticenter Study
In one paragraph

Article in The British journal of ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Peng Liu *School of Computer Science and Engineering & Shenzhen Institute for Advanced Study, University of Electronic Science and Technology of China, Chengdu, China.ORCID 0000-0002-4441-3638
Risa Higashita *Department of Computer Science and Engineering, Southern University of Science and Technology, Shenzhen, China.
Philip Yawen GuoDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Keiichiro OkamotoTomey Corporation, Nagoya, Japan.
Fei LiZhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-Sen University, Guangzhou, China.
Anwell NguyenDepartment of Ophthalmology, University of California San Francisco, San Francisco, California, USA.ORCID 0000-0002-1104-4194
Rei SakataDepartment of Ophthalmology, The University of Tokyo, Tokyo, Japan.
Lixin DuanSchool of Computer Science and Engineering & Shenzhen Institute for Advanced Study, University of Electronic Science and Technology of China, Chengdu, China.
Makoto AiharaDepartment of Ophthalmology, The University of Tokyo, Tokyo, Japan.
Shan LinDepartment of Ophthalmology, University of California San Francisco, San Francisco, California, USA.
Xiulan ZhangZhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-Sen University, Guangzhou, China.ORCID 0000-0002-9288-0767
Christopher Kai-Shun LeungDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China liuj@sustech.edu.cn cksleung.cuhk@gmail.com.ORCID 0000-0003-4862-777X
Jiang LiuDepartment of Computer Science and Engineering, Southern University of Science and Technology, Shenzhen, China liuj@sustech.edu.cn cksleung.cuhk@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo apply a deep learning model for automatic localisation of the scleral spur (SS) in anterior segment optical coherence tomography (AS-OCT) images and compare the reproducibility of anterior chamber angle (ACA) width between deep learning located SS (DLLSS) and manually plotted SS (MPSS).

methodsIn this multicentre, cross-sectional study, a test dataset comprising 5166 AS-OCT images from 287 eyes (116 healthy eyes with open angles and 171 eyes with primary angle-closure disease (PACD)) of 287 subjects were recruited from four ophthalmology clinics. Each eye was imaged twice by a swept-source AS-OCT (CASIA2, Tomey, Nagoya, Japan) in the same visit and one eye of each patient was randomly selected for measurements of ACA. The agreement between DLLSS and MPSS was assessed using the Euclidean distance (ED). The angle opening distance (AOD) of 750 µm (AOD750) and trabecular-iris space area (TISA) of 750 µm (TISA750) were calculated using the CASIA2 embedded software. The repeatability of ACA width was measured.

resultsThe mean age was 60.8±12.3 years (range: 30-85 years) for the normal group and 63.4±10.6 years (range: 40-91 years) for the PACD group. The mean difference in ED for SS localisation between DLLSS and MPSS was 66.50±20.54 µm and 84.78±28.33 µm for the normal group and the PACD group, respectively. The span of 95% limits of agreement between DLLSS and MPSS was 0.064 mm for AOD750 and 0.034 mm

conclusionDLLSS achieved comparable repeatability compared with MPSS for measurement of ACA.

Indexed as

Deep LearningGlaucoma, Angle-ClosureAgedAnterior ChamberAnterior Eye SegmentCross-Sectional StudiesGonioscopyHumansIntraocular PressureIrisMiddle AgedReproducibility of ResultsScleraTomography, Optical Coherenceanterior chamberglaucoma

Identifiers

PMID35091438
PMCPMC10313952

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.