ArticleMayo Clinic proceedings2022
Relationship Between Etiology of Cirrhosis and Survival Among Patients Hospitalized in Intensive Care Units.
Article in Mayo Clinic proceedings, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Development and validation of a prediction model for in-hospital mortality in intensive care unit patients with cirrhosis and sepsis: a multicentre retrospective cohort study.Frontiers in medicine · 2026Article
- Increased serum albumin corrected anion gap levels are associated with poor prognosis in septic patients with liver cirrhosis.Scientific reports · 2024Article
- Dynamic analysis of acute deterioration in chronic liver disease patients using modified quick sequential organ failure assessment.Clinical and molecular hepatology · 2024Article
- Predictive Factors for the Prognosis of Alcoholic Liver Cirrhosis.Medicina (Kaunas, Lithuania) · 2022Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
objectiveTo determine short-term outcomes of patients with alcohol-associated cirrhosis (ALC) admitted to the intensive care unit (ICU) compared with other etiologies of liver disease. In addition, we investigate whether quick sequential organ failure assessment accurately predicts presence of sepsis and in-hospital mortality in critically ill patients with various etiologies of cirrhosis.
methodsA retrospective cohort of 1174 consecutive patients with cirrhosis admitted to the ICU between January of 2006 and December of 2015 was analyzed. Outcomes of interest included survival rates within the ICU, post-ICU in-hospital, or at 30 days post-ICU discharge.
resultsFive hundred seventy-eight patients were found to have ALC with 596 in the non-ALC group. There was no significant difference in ICU mortality rates in ALC versus non-ALC cohorts (10.2% vs 11.7%, P=.40). However, patients with ALC had significantly higher post-ICU in-hospital death (10.0% vs 6.5%, P=.04) as well as higher mortality at 30-day post-ICU discharge (18.7% vs 11.2%, P<.001). Sustained alcohol abstinence did not offer survival advantage over nonabstinence. The predictive power for quick sequential organ failure assessment for sepsis and in-hospital mortality for patients with cirrhosis was limited.
conclusionCritically ill patients with ALC have decreased survival after ICU discharge compared with patients with other etiologies of cirrhosis, independent of alcohol abstinence.
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