Evidence map›Paper›PMID 35090717›Full record

ArticleJournal of pediatric surgery2022

Evaluating the association between obesity and discharge functional status after pediatric injury.

Shan L Ward, John M VanBuren, Rachel Richards, Richard Holubkov, Jessica S Alvey, Aaron R Jensen, Murray M Pollack, Randall S Burd

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Journal of pediatric surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Shan L WardDepartment of Pediatrics, UCSF Benioff Children's Hospitals Oakland, Oakland, CA, United States; Department of Pediatrics, UCSF Benioff Children's Hospitals San Francisco, San Francisco, CA, United States. Electronic address: shan.ward@ucsf.edu.
John M VanBurenDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, United States.
Rachel RichardsDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, United States.
Richard HolubkovDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, United States.
Jessica S AlveyDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, United States.
Aaron R JensenDepartment of Surgery, University of California San Francisco and Division of Pediatric Surgery, UCSF Benioff Children's Hospital Oakland, Oakland, CA, United States.
Murray M PollackDepartment of Pediatrics, Children's National Health System and the George Washington University School of Medicine and Health Sciences, Washington DC, United States.
Randall S BurdDivision of Trauma and Burn Surgery, Children's National Medical Center, Washington, DC, United States; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Assessment of Health-Related Quality of Life and Functional Outcomes after Pediatric Trauma Project Investigators.
University of Utah · USChildren's National · USUCSF Benioff Children's Hospital · USUniversity of California, San Francisco · US

Funding

Data Coordinating Center for the Collaborative Pediatric Critical Care Research NetworkU01HD049934 · NICHD · UNIVERSITY OF UTAH · PI DEAN, JONATHAN MICHAEL · 2005 to 2020
$35.2M
Mentored Career DevelopmentKL2TR001854 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Elizabeth Rhea Erwin Burner, Amy Elizabeth West · 2016 to 2026
$9.0M
Metoclopramide prevents PICU nosocomial infectionU10HD049983 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CARCILLO, JOSEPH A · 2005 to 2014
$3.1M
Collaborative Pediatric Critical Care Research Network (CPCCRN) at Children's NationalUG1HD049981 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI POLLACK, MURRAY MICHAEL, WESSEL, DAVID LLOYD · 2015 to 2020
$1.8M
Pediatric Critical Care Research Network at Children's Hospital of PhiladelphiaUG1HD063108 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI BERG, ROBERT ALLEN, ZUPPA, ATHENA F. · 2015 to 2020
$1.7M
Collaborative Pediatric Critical Care Research NetworkUG1HD050096 · NICHD · WAYNE STATE UNIVERSITY · PI MEERT, KATHLEEN L. · 2015 to 2020
$1.6M
Predicting Morbidity from Pediatric Critical CareU10HD063114 · NICHD · PHOENIX CHILDREN'S HOSPITAL · PI DALTON, HEIDI J, LUND, DENNIS P · 2010 to 2014
$1.4M
Collaborative Pediatric Critical Care Research Network - Clinical SiteRL1HD107773 · NICHD · CENTRAL MICHIGAN UNIVERSITY · PI KATHLEEN L. MEERT · 2021 to 2026
$862k
Los Angeles Center of the Collaborative Pediatric Critical Care Research NetworkUG1HD050012 · NICHD · CHILDREN'S HOSPITAL OF LOS ANGELES · PI NEWTH, CHRISTOPHER JOHN · 2015 to 2015
$17k
Collaborative Pediatric Critical Care Research NetworkUG1HD063106 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SHANLEY, THOMAS P. · 2015 to 2015
$16k
NCATS NIH HHS KL2 TR001854NICHD NIH HHS RL1 HD107773NICHD NIH HHS U01 HD049934NICHD NIH HHS U10 HD049983NICHD NIH HHS U10 HD063114NICHD NIH HHS UG1 HD049981NICHD NIH HHS UG1 HD050012NICHD NIH HHS UG1 HD050096NICHD NIH HHS UG1 HD063106NICHD NIH HHS UG1 HD063108
6 · The paper itself

Abstract

backgroundChildren with obesity frequently have functional impairment after critical illness. Although obesity increases morbidity risk after trauma, the association with functional outcomes in children is unknown.

objectiveTo evaluate the association of weight with functional impairment at hospital discharge in children with serious injuries.

methodsThis secondary analysis of a multicenter prospective study included children <15 years old with a serious injury. Four weight groups, underweight, healthy weight, overweight, and obesity/severe obesity were defined by body mass index z-scores. The functional status scale (FSS) measured impairment across six functional domains before injury and at hospital discharge. New domain morbidity was defined as a change ≥2 points. The association between weight and functional impairment was determined using logistic regression adjusting for demographics, physiological measures, injury details, presence of a severe head injury, and physical abuse.

resultsAlthough most patients discharged with good/unchanged functional status, new domain morbidity occurred in 74 patients (17%). New FSS domain morbidity occurred in 13% of underweight, 14% of healthy weight, 15% of overweight, and 26% of obese/severe obese patients. Compared to healthy weight patients, those with obesity had more frequent new domain morbidity (p = 0.01), while the other weight groups had similar morbidity. However, after adjustment for confounders, weight was not associated with new functional morbidity at discharge.

conclusionPatients with obesity have greater frequency of new domain morbidity after a serious injury; however, after accounting for injury characteristics, weight group is not independently associated with new functional morbidity at hospital discharge after injury in children. LEVEL OF EVIDENCE: III.

Indexed as

Patient DischargePediatric ObesityAdolescentBody Mass IndexChildFunctional StatusHumansObesityOverweightProspective StudiesThinnessChildhood obesityFunctional outcomesInjuryTrauma

Identifiers

PMID35090717
PMCPMC9808528
OpenAlexW4210587340

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.