Evidence map›Paper›PMID 35090684›Full record

ArticleAmerican journal of surgery2022

Disparities in timely treatment among young women with breast cancer.

Urvish Jain, Bhav Jain, Oluwadamilola M Fayanju, Fumiko Chino, Edward Christopher Dee

Open access · greenAbstract read
In one paragraph

Article in American journal of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Urvish JainUniversity of Pittsburgh, Pittsburgh, PA, USA.
Bhav JainMassachusetts Institute of Technology, Cambridge, MA, USA.
Oluwadamilola M FayanjuDepartment of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Rena Rowan Breast Center, Abramson Cancer Center, Penn Medicine, Philadelphia, PA, USA.
Fumiko ChinoDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: ChinoF@mskcc.org.
Edward Christopher DeeDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: deee1@mskcc.org.
Memorial Sloan Kettering Cancer Center · USMassachusetts Institute of Technology · USPenn Center for AIDS Research · USUniversity of Pittsburgh · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Using Modifiable Risk Factors to Predict Inferior Care and Survival after Breast Cancer Diagnosis: A Novel Approach to Addressing Health DisparitiesK08CA241390 · NCI · UNIVERSITY OF PENNSYLVANIA · PI FAYANJU, OLUWADAMILOLA M. · 2019 to 2023
$1.1M
NCI NIH HHS K08 CA241390NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundAlthough evidence suggests worse breast cancer-specific survival associated with treatment delay beyond 90 days, little is known regarding the sociodemographic predictors of delays in cancer-directed surgery among young women with breast cancer. This is particularly notable, given that 5-10% of new diagnoses occur in younger women aged <40 years, commonly with more aggressive features than in older women.

methodsWe used the National Cancer Database (2004-2017) to assess sociodemographic disparities in delay of upfront surgery beyond 90 days among young women with non-metastatic breast cancer, using multivariable logistic regression and predictive marginal modeling.

resultsBlack women experienced treatment delays more frequently than white women (aOR: 1.93 [95% CI: 1.76-2.11], p < 0.001). Adjusted rates of treatment delay were 4.91% [95% CI: 4.51%-5.30%] and 2.60% [95% CI: 2.47%-2.74%] for Black and white women, respectively, and 2.97% [95% CI: 2.83%-3.12%], 2.36% [95% CI: 2.03%-2.68%], and 1.18% [95% CI: 0.54%-1.81%] for women from metro, urban, and rural areas, respectively.

conclusionThese results suggest that improving access to timely treatment may be leveraged as a means through which to lessen the breast cancer disparities experienced by Black women.

Indexed as

Breast NeoplasmsWhite PeopleAgedBlack or African AmericanFemaleHealthcare DisparitiesHumansTime-to-Treatmentadolescents and young adults with cancerAYABreast cancerbreast surgerycancer disparitiesracial disparitiesrural health disparitiessurgerytreatment delay

Identifiers

PMID35090684
PMCPMC9304449
OpenAlexW4206953151

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.