ArticleDiabetology & metabolic syndrome2022
Assessment of subclinical left ventricle myocardial dysfunction using global myocardial work in type 2 diabetes mellitus patients with preserved left ventricle ejection fraction.
Article in Diabetology & metabolic syndrome, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Effects of aerobic exercise on integrated cardiovascular health and energy metabolism in patients with type 2 diabetes mellitus: study protocol for a randomized controlled trial.Frontiers in endocrinology · 2026Trial
- Prediabetes and diabetes exacerbated cardiac systolic function in obese patients at the subclinical stage: insights from global longitudinal strain and myocardial work.Diabetology & metabolic syndrome · 2026Article
- Ventricular Mechanics and Serum Biomarkers as Predictors of Aortic Valve Replacement in Severe Aortic Stenosis.Vascular health and risk management · 2026Article
- The Contribution of Echocardiography to the Diagnosis and Prognosis Stratification of Diabetic Cardiomyopathy.Diagnostics (Basel, Switzerland) · 2025Review
- Arterial Stiffness and Early Cardiac Dysfunction in Type 2 Diabetes Mellitus: A Potential Role for 25 OH Vitamin D3 Deficiency.Medicina (Kaunas, Lithuania) · 2025Article
- Evaluation of left ventricular systolic function in type 2 diabetes mellitus patients with and without peripheral vascular disease.World journal of diabetes · 2024Article
- Echocardiographic Myocardial Work: A Novel Method to Assess Left Ventricular Function in Patients with Coronary Artery Disease and Diabetes Mellitus.Medicina (Kaunas, Lithuania) · 2024Review
- Evaluation of subclinical left ventricular systolic dysfunction in obese patients by global myocardial work.Diabetology & metabolic syndrome · 2023Article
- Assessment of subclinical left ventricular myocardial systolic dysfunction in type 2 diabetes mellitus patients with or without hypertension by global and segmental myocardial work.Diabetology & metabolic syndrome · 2023Article
- The Role of Echocardiography in Evaluating Cardiovascular Diseases in Patients with Diabetes Mellitus.Diabetes & metabolism journal · 2023Review
- Assessment of left ventricular function in patients with type 2 diabetes mellitus by non-invasive myocardial work.Frontiers in endocrinology · 2023Article
- Oxidative Stress and Left Ventricular Performance in Patients with Different Glycometabolic Phenotypes.Nutrients · 2022Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThe purpose of this study was to assess subclinical left ventricle (LV) myocardial dysfunction using global myocardial work (MW) in type 2 diabetes mellitus (T2DM) patients with preserved left ventricle ejection fraction (LVEF).
methodsSixty T2DM patients and 60 normal controls were enrolled in the study. Apical 4-, 3- and 2-chamber views were acquired by two-dimensional echocardiography. Peak systolic myocardial global longitudinal strain (GLS), global myocardial work index (GWI), global constructive work (GCW), global wasted work (GWW), and myocardial work efficiency (GWE) were determined by speckle-tracking echocardiography (STE).
resultsThe GLS values in the T2DM patients were significantly lower than those in normal controls (p < 0.001). The GWW in T2DM patients was significantly greater than that in normal controls, while GWI, GCW and GWE was significantly lower (p < 0.001). Receiver operating characteristic (ROC) analysis showed there were no significant different difference between GWW, GWE and GLS in the area under the curves (AUCs). In T2DM patients, fasting plasma glucose was positively correlated with GWW but negatively correlated with GWE, and GLS was negatively correlated with GWI and GCW.
conclusionFrom the research, we found that global MW as new technique could detect the subclinical LV myocardial dysfunction and confirm that the impaired LV function in T2DM patients with preserved LV systolic function.
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