Evidence map›Paper›PMID 35090413›Full record

ArticleBMC surgery2022

Risk factors and management strategies for cerebrospinal fluid leakage following lumbar posterior surgery.

Jin Tang, Qilin Lu, Ying Li, Congjun Wu, Xugui Li, Xuewen Gan, Wei Xie

Open access · goldAbstract read
In one paragraph

Article in BMC surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  5. Rivaroxaban versus enoxaparin as thromboprophylaxis in degenerative spine surgery: a randomized blinded non-inferiority study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
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  7. Incidental durotomy during tubular microdiscectomy does not preclude same-day discharge.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
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  8. Article
  9. Article
  10. [Research status of dural injury types and repair].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jin Tang *Hubei 672 Orthopaedics Hospital of Integrated Chinese & Western Medicine, No. 279 Luoyu Road, Hongshan District, Wuhan, 430079, Hubei, China.
Qilin Lu *Hubei 672 Orthopaedics Hospital of Integrated Chinese & Western Medicine, No. 279 Luoyu Road, Hongshan District, Wuhan, 430079, Hubei, China.
Ying LiHubei 672 Orthopaedics Hospital of Integrated Chinese & Western Medicine, No. 279 Luoyu Road, Hongshan District, Wuhan, 430079, Hubei, China.
Congjun WuHubei 672 Orthopaedics Hospital of Integrated Chinese & Western Medicine, No. 279 Luoyu Road, Hongshan District, Wuhan, 430079, Hubei, China.
Xugui LiHubei 672 Orthopaedics Hospital of Integrated Chinese & Western Medicine, No. 279 Luoyu Road, Hongshan District, Wuhan, 430079, Hubei, China.
Xuewen GanHubei 672 Orthopaedics Hospital of Integrated Chinese & Western Medicine, No. 279 Luoyu Road, Hongshan District, Wuhan, 430079, Hubei, China.
Wei XieHubei 672 Orthopaedics Hospital of Integrated Chinese & Western Medicine, No. 279 Luoyu Road, Hongshan District, Wuhan, 430079, Hubei, China. spine672@126.com.
Integrated Chinese Medicine (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze the risk factors of cerebrospinal fluid leakage (CSFL) following lumbar posterior surgery and summarize the related management strategies.

methodsA retrospective analysis was performed on 3179 patients with CSFL strategies lumbar posterior surgery in our hospital from January 2019 to December 2020. There were 807 cases of lumbar disc hemiation (LDH), 1143 cases of lumbar spinal stenosi (LSS), 1122 cases of lumbar spondylolisthesis(LS), 93 cases of lumbar degenerative scoliosis(LDS),14 cases of lumbar spinal benign tumor (LST). Data of gender, age, body mass index(BMI), duration of disease, diabete, smoking history, preoperative epidural steroid injection, number of surgical levels, surgical methods (total laminar decompression, fenestration decompression), revision surgery, drainage tube removal time, suture removal time, and complications were recorded.

resultsThe incidence of 115 cases with cerebrospinal fluid leakage, was 3.6% (115/3179).One-way ANOVA showed that gender, body mass index (BMI), smoking history, combined with type 2 diabetes and surgical method had no significant effect on CSFL (P > 0.05). Age, type of disease, duration of disease, preoperative epidural steroid injection, number of surgical levels and revision surgery had effects on CSFL (P < 0.05). Multivariate Logistic regression analysis showed that type of disease, preoperative epidural steroid injection, number of surgical levels and revision surgery were significantly affected CSFL (P < 0.05).Drainage tube removal time of CSFL patients ranged from 7 to 11 days, with an average of 7.1 ± 0.5 days, drainage tube removal time of patients without CSFL was 1-3 days, with an average of 2.0 ± 0.1 days, and there was a statistical difference between the two groups (P < 0.05).The removal time of CSFL patients was 12-14 days, with an average of 13.1 ± 2.7 days, and the removal time of patients without CSFL was 10-14 days, with an average of 12.9 ± 2.2 days, there was no statistically significant difference between the two groups (P > 0.05).

conclusionType of disease, preoperative epidural steroid injection, number of surgical levels and revision surgery were the risk factors for CSFL. Effective prevention were the key to CSFL in lumbar surgery. Once appear, CSFL can also be effectively dealt without obvious adverse reactions after intraoperative effectively repair dural, head down, adequate drainage after operation, the high position, rehydration treatment, and other treatments.

Indexed as

Diabetes Mellitus, Type 2Cerebrospinal Fluid LeakHumansPostoperative ComplicationsRetrospective StudiesRisk FactorsCerebrospinal fluid leakage (CSFL)Logistic regression analysisLumbar posterior surgeryManagement strategyRisk factor

Identifiers

PMID35090413
PMCPMC8800267
OpenAlexW4210698879

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.