Evidence map›Paper›PMID 35089896›Full record

ArticleDermatitis : contact, atopic, occupational, drug

Cutaneous Comorbidities Associated With Atopic Dermatitis in Israel: A Retrospective Real-World Data Analysis.

Yael A Leshem, Philip B Sugerman, Clara Weil, Gabriel Chodick, Huifang Liang, Hongwei Wang, Brian Calimlim, Ana Dorfman, Varda Shalev, Dan Ben Amitai

Open access · greenAbstract read
In one paragraph

Article in Dermatitis : contact, atopic, occupational, drug. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Yael A Leshem
Philip B Sugerman
Clara WeilMaccabi Institute for Research and Innovation (Maccabitech), Maccabi Healthcare Services, Tel Aviv.
Gabriel Chodick
Huifang LiangAbbVie Inc., North Chicago, IL.
Hongwei WangAbbVie Inc., North Chicago, IL.
Brian CalimlimAbbVie Inc., North Chicago, IL.
Ana DorfmanAbbVie Biopharmaceuticals Ltd., Hod Hasharon.
Varda Shalev
Dan Ben Amitai
AbbVie (United States) · USMaccabi Institute for Health Services Research · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with atopic dermatitis (AD) are susceptible to infectious and inflammatory cutaneous comorbidities.

objectiveThe aim of the study was to describe the prevalence of cutaneous comorbidities associated with AD, including their relationship with AD severity.

methodsA retrospective cross-sectional analysis was performed using the Israeli Maccabi Healthcare Services database. Prevalent AD cases on December 31, 2017, were diagnosed with AD at any time since 1998 and had 1 or more recent (2013-2017) AD diagnoses. Dispensed AD treatments within 5 or fewer years served as a surrogate for AD severity. Cutaneous comorbidities in AD cases were compared with non-AD controls matched 1:1 on age, sex, and residential area. Among adults, comorbidities were compared across AD severity using multinomial logistic regression.

resultsThe eligible population included 94,483 patients with mild (57.7%), moderate (36.2%), or severe (6.1%) AD, and 94,483 matched non-AD controls. Skin infections, inflammatory skin conditions, cutaneous manifestations of AD, and sweat gland disorders were more prevalent ( P < 0.001) in patients with AD than in controls. Most cutaneous comorbidities that were more prevalent in adult patients with AD were also significantly ( P < 0.001) associated with AD severity.

conclusionsThis study suggests that AD is associated with many infectious and inflammatory cutaneous comorbidities and highlights the relationship between AD severity and comorbidity prevalence.

Indexed as

Dermatitis, AtopicAdultComorbidityCross-Sectional StudiesData AnalysisHumansIsraelRetrospective Studies

Identifiers

PMID35089896
PMCPMC9674444
OpenAlexW4210309568

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.