Evidence map›Paper›PMID 35089648›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2022

Long-term predialysis blood pressure variability and outcomes in hemodialysis patients.

Jingjuan Yang, Jian Huang, Biying Yu, Qian Zhang, Shanshan Zhang, Longlong Wu, Lin Luo, Lizhu Li, Li Li, Fei Han and 2 more

Abstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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  11. Long-term predialysis blood pressure variability and outcomes in hemodialysis patients.Journal of clinical hypertension (Greenwich, Conn.) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jingjuan YangDepartment of Nephrology, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China.
Jian HuangDepartment of Nephrology, Central Hospital of Jinhua, Jinhua, China.
Biying YuDepartment of Nephrology, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China.
Qian ZhangKidney Disease Center, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Shanshan ZhangDepartment of Nephrology, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China.
Longlong WuDepartment of Nephrology, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China.
Lin LuoDepartment of Nephrology, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China.
Lizhu LiDepartment of Nephrology, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China.
Li LiDepartment of Nephrology, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China.
Fei HanKidney Disease Center, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
En Yin LaiKidney Disease Center, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yi YangDepartment of Nephrology, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China.ORCID 0000-0002-6285-0807

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blood pressure variability (BPV) is significantly associated with cardiovascular diseases (CVD) and mortality in hemodialysis patients. However, the relationship between blood pressure and CVD in hemodialysis patients is complex and affected by many factors. The present study aimed to assess the association of long-term predialysis BPV with all-cause mortality and major adverse cardiovascular events (MACE). One thousand seven hundred twenty-seven patients receiving maintenance hemodialysis were recruited in nine hemodialysis centers. Predialysis BPV was assessed over 1-year intervals. Outcomes included all-cause mortality and MACE during follow-up periods. The mean age of the final cohort was 59 years, of which 57% were males. Greater predialysis systolic BPV was associated with an increased risk of all-cause mortality (adjusted hazard ratio, 1.101; 95% confidence intervals 1.064-1.140) and MACE (adjusted hazard ratio, 1.091; 95% confidence intervals 1.059-1.125). Results were similar when systolic BPV was stratified by baseline systolic blood pressure. In conclusion, greater predialysis BPV among hemodialysis patients was associated with all-cause mortality and MACE. Strategies to reduce blood pressure variability might be beneficial for hemodialysis patients.

Indexed as

Cardiovascular DiseasesHypertensionBlood PressureBlood Pressure Monitoring, AmbulatoryHumansMaleMiddle AgedRenal DialysisRisk Factorsall-cause mortalityhemodialysisMACEpredialysis blood pressure

Identifiers

PMID35089648
PMCPMC8845477

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.