Evidence map›Paper›PMID 35089531›Full record

ArticleInternational journal of hematology2022

Paravertebral extramedullary hematopoiesis in a case of myelodysplastic syndrome with ring sideroblasts and an SF3B1 mutation.

Chie Asou, Tomoya Maeda, Maho Ishikawa, Daisuke Okamura, Mika Kohri, Naoki Takahashi, Kunihiro Tsukasaki, Hirozo Sakaguchi, Tsugumi Satoh, Hidekazu Kayano and 2 more

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in International journal of hematology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Chie AsouDepartment of Hematology, International Medical Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan. achie5@saitama-med.ac.jp.ORCID http://orcid.org/0000-0002-3104-7739
Tomoya MaedaDepartment of Hematology, International Medical Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan.ORCID http://orcid.org/0000-0002-3107-5991
Maho IshikawaDepartment of Hematology, International Medical Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan.
Daisuke OkamuraDepartment of Hematology, International Medical Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan.
Mika KohriDepartment of Hematology, International Medical Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan.
Naoki TakahashiDepartment of Hematology, International Medical Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan.
Kunihiro TsukasakiDepartment of Hematology, International Medical Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan.
Hirozo SakaguchiDepartment of Thoracic Surgery, International Medical Center, Saitama Medical University, Saitama, Japan.
Tsugumi SatohDepartment of Pathology, International Medical Center, Saitama Medical University, Saitama, Japan.
Hidekazu KayanoFaculty of Health and Medical Care, Saitama Medical University, Saitama, Japan.
Akira MatsudaDepartment of Hematology, International Medical Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan.
Norio AsouDepartment of Hematology, International Medical Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan.
Saitama Medical University · JP

Funding

the Japan Agency for Medical Research and Development JP21ck0106620
6 · The paper itself

Abstract

We present the case of a 56-year-old male patient with paravertebral extramedullary hematopoiesis (EMH) secondary to myelodysplastic syndrome with ring sideroblasts and multilineage dysplasia. In a routine health checkup over 5 years prior, he presented with asymptomatic mild anemia and a posterior mediastinal mass. Pathological and cytomorphological findings of the resected paravertebral mass were similar to those of his bone marrow specimen, and included cellularity with erythroid hyperplasia, multilineage dysplastic changes, and the presence of ring sideroblasts. A concordant SF3B1 mutation was detected in both bone marrow and paravertebral mass samples, suggesting that the EMH cells were derived from the bone marrow.

Indexed as

Hematopoiesis, ExtramedullaryMyelodysplastic SyndromesHumansMaleMiddle AgedMutationPhosphoproteinsRNA Splicing FactorsPhosphoproteinsRNA Splicing FactorsSF3B1 protein, humanExtramedullary hematopoiesisMyelodysplastic syndromesParavertebral regionRing sideroblastsSF3B1 mutation

Identifiers

PMID35089531
OpenAlexW4210530954

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.