ReviewEnvironmental science and pollution research international2022
Current research scenario for biological effect of exogenous factors on microcystin synthesis.
Review in Environmental science and pollution research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 13 citations in OpenAlex.
- Field-Based Mesocosm Evidence for the Role of Natural Nutrient Sources in Cyanobacterial Blooms.Environmental analysis, health and toxicology · 2026Article
- Combined Effects of Irradiation, Nutrients, and Cyanobacterial Composition on Microcystin Concentration in Chinese Plateau Lakes.Environment & health (Washington, D.C.) · 2025Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In natural water bodies, numerous cyanobacteria have the potential to intracellularly synthesize cyanotoxins, among which microcystin (MC) is the ubiquitous toxin that has been well known to be carcinogenic for hepatocytes. MC synthesis is a complex process, which involves about 10 non-ribosomal proteins encoded by the mcy gene cluster. In the natural environments containing MC-producing cyanobacteria, a variety of external factors can affect the generation of MC by mediating the expression of synthesizing genes. These factors can be generally divided into biotic factors (e.g., daphnia, virioplankton, MC-degrading bacteria, algicidal bacteria) and abiotic factors (e.g., nutrients, physical factors, chemicals, phytochemicals, essential trace elements), which are of great significance to the effective reduction of MC. Furthermore, comparison of MC-synthesizing genes in different cyanobacterial strains was performed, and the related factors affecting MC synthesis were summarized. Then, the problems and gaps regarding the biological effect of exogenous factors on microcystin synthesis were discussed. This review article may provide new ideas for addressing the challenges and bottlenecks of MC management.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.