Evidence map›Paper›PMID 35089466›Full record

ReviewGlycoconjugate journal2022

Role of glycosyltransferases in carcinogenesis; growth factor signaling and EMT/MET programs.

Motoko Takahashi, Yoshihiro Hasegawa, Kento Maeda, Masato Kitano, Naoyuki Taniguchi

Open access · hybridAbstract readReview
In one paragraph

Review in Glycoconjugate journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Regulation of Glycosylation in Bone Metabolism.International journal of molecular sciences · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Motoko TakahashiDepartment of Biochemistry, Sapporo Medical University School of Medicine, South-1 West-17, Chuo-ku, Hokkaido, 060-8556, Japan. takam@sapmed.ac.jp.ORCID 0000-0002-2112-6142
Yoshihiro HasegawaDepartment of Biochemistry, Sapporo Medical University School of Medicine, South-1 West-17, Chuo-ku, Hokkaido, 060-8556, Japan.
Kento MaedaDepartment of Glyco-Oncology and Medical Biochemistry, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan.
Masato KitanoDepartment of Glyco-Oncology and Medical Biochemistry, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan.
Naoyuki TaniguchiDepartment of Glyco-Oncology and Medical Biochemistry, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan. tani52@wd5.so-net.ne.jp.
Osaka International Cancer Institute · JPSapporo Medical University · JPOsaka International Cancer Institute · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The glycosylation of cell surface receptors has been shown to regulate each step of signal transduction, including receptor trafficking to the cell surface, ligand binding, dimerization, phosphorylation, and endocytosis. In this review we focus on the role of glycosyltransferases that are involved in the modification of N-glycans, such as the effect of branching and elongation in signaling by various cell surface receptors. In addition, the role of those enzymes in the EMT/MET programs, as related to differentiation and cancer development, progress and therapy resistance is discussed.

Indexed as

GlycosyltransferasesN-AcetylglucosaminyltransferasesCarcinogenesisHumansIntercellular Signaling Peptides and ProteinsSignal TransductionGlycosyltransferasesIntercellular Signaling Peptides and ProteinsN-AcetylglucosaminyltransferasesCell surface receptorCollectinEGFREMT programsErbB receptorsFut8GM3GnT-IIIGnT-VST6Gal1

Identifiers

PMID35089466
PMCPMC8795723
OpenAlexW4212935756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.