Evidence map›Paper›PMID 35089366›Full record

ArticleDer Nervenarzt2022

[The new Parkinson's disease pain classification system (PD-PCS)].

V Mylius, S Perez Lloret, C S Brook, M T Krüger, S Hägele-Link, R Gonzenbach, J Kassubek, S Bohlhalter, J P Lefaucheur, L Timmermann and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Der Nervenarzt, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 7 countries.

V MyliusKlinik für Neurologie und Neurorehabilitation, Kliniken Valens, Valens, Schweiz. Veit.Mylius@kliniken-valens.ch.
S Perez LloretBiomedical Research Center (CAECIHS-UAI), National Research Council (CONICET), Buenos Aires, Argentinien.
C S BrookKlinik für Neurologie und Neurorehabilitation, Kliniken Valens, Valens, Schweiz.
M T KrügerKlinik für Neurochirurgie, Kantonsspital St. Gallen, St. Gallen, Schweiz.
S Hägele-LinkKlinik für Neurologie, Kantonsspital St. Gallen, St. Gallen, Schweiz.
R GonzenbachKlinik für Neurologie und Neurorehabilitation, Kliniken Valens, Valens, Schweiz.
J KassubekKlinik für Neurologie, Universität Ulm, Ulm, Deutschland.
S BohlhalterNeurozentrum, Luzerner Kantonsspital and Universität Zürich, Luzern, Schweiz.
J P LefaucheurEA 4391, Unité de Neurophysiologie Clinique, Hôpital Henri Mondor, Assistance Publique - Hôpitaux de Paris, Faculté de Médecine de Créteil, Université Paris-Est-Créteil, Créteil, Frankreich.
L TimmermannKlinik für Neurologie, Philipps Universität Marburg, Marburg, Deutschland.
G KägiKlinik für Neurologie, Kantonsspital St. Gallen, St. Gallen, Schweiz.
F BruggerKlinik für Neurologie, Kantonsspital St. Gallen, St. Gallen, Schweiz.
D Ciampi de AndradePain Center, LIM-62, Departamento de Neurologia da Faculdade de Medicina da Universidade de Sao Paulo, Hospital das Clínicas, Sao Paulo, Brasilien.
J C MöllerKlinik für Neurologie, Philipps Universität Marburg, Marburg, Deutschland.
Kantonsspital St. Gallen · CHPhilipps University of Marburg · DEValens Clinics · CHConsejo Nacional de Investigaciones Científicas y Técnicas · ARHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRLuzerner Kantonsspital · CHUniversität Ulm · DEUniversité Paris-Est Créteil · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic pain is a common non-motor symptom in patients with Parkinson's disease (PD).

aimTo facilitate the diagnosis of pain in PD, we developed a new classification system the Parkinson's disease pain classification system (PD-PCS) and translated the corresponding validated questionnaire into German.

methodsA causal relationship of the respective pain syndrome with PD can be determined by four questions before assigning it hierarchically into one of three pain categories (neuropathic, nociceptive and nociplastic).

resultsIn the initial validation study 77% of the patients (122/159) had PD-associated pain comprising 87 (55%) with nociceptive, 36 (22%) with nociplastic and 24 (16%) with neuropathic pain. The study revealed a high validity of the questionnaire and a moderate intrarater and interrater reliability. The questionnaire has been adapted into German and employed in 30 patients. DISCUSSION: The PD-PCS questionnaire is a valid and reliable tool to determine the relationship of a pain syndrome with PD before classifying it according to the underlying category, facilitating further diagnostics and treatment.

Indexed as

NeuralgiaParkinson DiseaseHumansPain MeasurementReproducibility of ResultsSurveys and QuestionnairesNeuropathicNociceptiveNociplasticPainQuestionnaire

Identifiers

PMID35089366
PMCPMC9534980
OpenAlexW4210435701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.