Evidence map›Paper›PMID 35089362›Full record

ReviewDer Urologe. Ausg. A2022

[Metastatic urothelial carcinoma-guideline-based therapy and new options].

Günter Niegisch, Gunhild von Amsberg, Marc Rehlinghaus, Camilla M Grunewald, Margitta Retz

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Urologe. Ausg. A, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Günter NiegischMedizinische Fakultät, Klinik für Urologie, Bereich Konservative Urologische Onkologie, Heinrich-Heine-Universität, Moorenstr. 5, 40225, Düsseldorf, Deutschland. uro-onkologie@med.uni-duesseldorf.de.
Gunhild von AmsbergInterdisziplinäreArbeitsgruppe HarnblasenCarcinom (IABC) der DKG.
Marc RehlinghausMedizinische Fakultät, Klinik für Urologie, Bereich Konservative Urologische Onkologie, Heinrich-Heine-Universität, Moorenstr. 5, 40225, Düsseldorf, Deutschland.
Camilla M GrunewaldMedizinische Fakultät, Klinik für Urologie, Bereich Konservative Urologische Onkologie, Heinrich-Heine-Universität, Moorenstr. 5, 40225, Düsseldorf, Deutschland.
Margitta RetzInterdisziplinäreArbeitsgruppe HarnblasenCarcinom (IABC) der DKG.
Heinrich Heine University Düsseldorf · DEKlinikum rechts der Isar · DEMartini-Klinik · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the approval of immuno-oncological therapies with immune checkpoint inhibitors, the treatment of metastatic urothelial carcinoma has become more complex in all lines of therapy. Thus, in first-line treatment, immunotherapy alone or immune maintenance therapy following platinum-based chemotherapy can be applied in addition to treatment with platinum-based combination therapies alone. In addition to the approval status and guideline recommendation, patient-specific factors such as comorbidities as well as patient preference must always be considered when choosing a therapy. In the following, we summarize the current data on treatment options in the first-line therapy of metastatic urothelial carcinoma and illustrate their practical application using a patient example.

Indexed as

Carcinoma, Transitional CellUrinary Bladder NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsHumansImmune Checkpoint InhibitorsImmunotherapyImmune Checkpoint InhibitorsChemotherapyFGFRImmune checkpoint inhibitorsLymph nodesPD-L1

Identifiers

PMID35089362
OpenAlexW4210501626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.