ArticleThe British journal of surgery2022
Wire- and magnetic-seed-guided localization of impalpable breast lesions: iBRA-NET localisation study.
Article in The British journal of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Wire-Free, Nonradioactive Localization Techniques to Guide Surgical Excision of Nonpalpable Breast Tumours: A Health Technology Assessment.Ontario health technology assessment series · 2023Pooled it
- Magnetic seed versus guidewire-based breast cancer localization with magnetic lymph node detection: cost-minimization analysis.The British journal of surgery · 2025Trial
- Article
- A Single-Institution Comparative Analysis of Bracketed Localization for Partial Mastectomy Using Traditional Wire and Wireless Methods.Annals of surgical oncology · 2026Article
- Intraoperative measurement of breast-conserving surgery margins: surgical application.Breast cancer research : BCR · 2026Review
- Adoption of nonwire localisation devices in UK breast units: an iBRA-NET survey to assess changes in practice.Annals of the Royal College of Surgeons of England · 2026Article
- Radioguided occult lesion localisation for wide local excision, excision biopsies and in combination with radioisotope sentinel lymph node localisation (SNOLL) - 10 year experience of a single centre.Surgery in practice and science · 2026Article
- Article
- A 3D-printed screw mechanism as an alternative method to prevent wire migration in nonpalpable breast lesion localization.BMC surgery · 2025Article
- Intraoperative ultrasound-guided wire(IOUS-wire) localization biopsy versus preoperative fine needle aspiration cytology(FNAC) for early breast cancer with clinically positive nodes, a retrospective cohort study.World journal of surgical oncology · 2025Article
- Magnetic surgical marker navigation for excision of non-palpable ultrasound visible breast lesions: first 200 cases in a French cancer center.Scientific reports · 2025Article
- The Era "or Error" of Second Localization Procedures.The breast journal · 2025Article
- Surgical marker navigation system in breast conserving surgery and excision of non-palpable lesions: first Spanish single-center experience.Breast cancer research and treatment · 2024Observational
- Resection Ratios and Tumor Eccentricity in Breast-Conserving Surgery Specimens for Surgical Accuracy Assessment.Cancers · 2024Article
- The association of breast surgery ASPIRE: breast pain pathway rapid evaluation project - study protocol.International journal of surgery protocols · 2024Article
- Magnetic Seed vs Guidewire Breast Cancer Localization With Magnetic Lymph Node Detection: A Randomized Clinical Trial.JAMA surgery · 2024Article
- Breast-Conserving Surgery Guided with Magnetic Seeds vs. Wires: A Single-Institution Experience.Cancers · 2024Article
- Breast and axillary marking in the neoadjuvant setting: survey results from experts of the Brazilian society of mastology.Frontiers in oncology · 2024Article
- Locoregional Therapy: From Mastectomy to Reconstruction, Targeted Surgery, and Ultra-Hypofractionated Radiotherapy.Breast care (Basel, Switzerland) · 2023Review
- Comparison of Wire and Non-Wire Localisation Techniques in Breast Cancer Surgery: A Review of the Literature with Pooled Analysis.Medicina (Kaunas, Lithuania) · 2023Review
Corrections and comments
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Authors and funding
17 authors at 14 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWire localization is historically the most common method for guiding excision of non-palpable breast lesions, but there are limitations to the technique. Newer technologies such as magnetic seeds may allow some of these challenges to be overcome. The aim was to compare safety and effectiveness of wire and magnetic seed localization techniques.
methodsWomen undergoing standard wire or magnetic seed localization for non-palpable lesions between August 2018 and August 2020 were recruited prospectively to this IDEAL stage 2a/2b platform cohort study. The primary outcome was effectiveness defined as accurate localization and removal of the index lesion. Secondary endpoints included safety, specimen weight and reoperation rate for positive margins.
resultsData were accrued from 2300 patients in 35 units; 2116 having unifocal, unilateral breast lesion localization. Identification of the index lesion in magnetic-seed-guided (946 patients) and wire-guided excisions (1170 patients) was 99.8 versus 99.1 per cent (P = 0.048). There was no difference in overall complication rate. For a subset of patients having a single lumpectomy only for lesions less than 50 mm (1746 patients), there was no difference in median closest margin (2 mm versus 2 mm, P = 0.342), re-excision rate (12 versus 13 per cent, P = 0.574) and specimen weight in relation to lesion size (0.15 g/mm2versus 0.138 g/mm2, P = 0.453).
conclusionMagnetic seed localization demonstrated similar safety and effectiveness to those of wire localization. This study has established a robust platform for the comparative evaluation of new localization devices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.