Evidence map›Paper›PMID 35089141›Full record

ArticleJournal of medical Internet research2022

Identifying Information Gaps in Electronic Health Records by Using Natural Language Processing: Gynecologic Surgery History Identification.

Sungrim Moon, Luke A Carlson, Ethan D Moser, Bhavani Singh Agnikula Kshatriya, Carin Y Smith, Walter A Rocca, Liliana Gazzuola Rocca, Suzette J Bielinski, Hongfang Liu, Nicholas B Larson

Abstract read
In one paragraph

Article in Journal of medical Internet research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. [Medical education and artificial intelligence: perspectives and ethical challenges].Revista medica del Instituto Mexicano del Seguro Social · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sungrim MoonDepartment of Artificial Intelligence and Informatics, Mayo Clinic, Rochester, MN, United States.ORCID 0000-0002-9191-3897
Luke A CarlsonDepartment of Artificial Intelligence and Informatics, Mayo Clinic, Rochester, MN, United States.ORCID 0000-0002-3672-3548
Ethan D MoserDivision of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, United States.ORCID 0000-0003-1094-9108
Bhavani Singh Agnikula KshatriyaDepartment of Artificial Intelligence and Informatics, Mayo Clinic, Rochester, MN, United States.ORCID 0000-0003-1594-5632
Carin Y SmithDivision of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, United States.ORCID 0000-0002-3610-6945
Walter A RoccaDivision of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, United States.ORCID 0000-0002-1832-7664
Liliana Gazzuola RoccaDivision of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, United States.ORCID 0000-0002-9945-3928
Suzette J BielinskiDivision of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, United States.ORCID 0000-0002-2905-5430
Hongfang LiuDepartment of Artificial Intelligence and Informatics, Mayo Clinic, Rochester, MN, United States.ORCID 0000-0003-2570-3741
Nicholas B LarsonDivision of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, United States.ORCID 0000-0002-3468-4215

Funding

Women's Cancer ProgramP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI Felicity Enders · 1985 to 2026
$151.3M
Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's DiseaseU54AG044170 · NIA · MAYO CLINIC ROCHESTER · PI KAPOOR, EKTA · 2018 to 2022
$7.7M
Open Health Natural Language Processing CollaboratoryU01TR002062 · NCATS · MAYO CLINIC ROCHESTER · PI JIANG, XIAOQIAN, LIU, HONGFANG · 2017 to 2021
$7.6M
Semi-structured Information Retrieval in Clinical Text for Cohort IdentificationR01LM011934 · NLM · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI HERSH, WILLIAM R, LIU, HONGFANG · 2014 to 2025
$5.1M
Reproductive risk factors for Alzheimer's disease dementia and pathologyRF1AG055151 · NIA · MAYO CLINIC ROCHESTER · PI MIELKE, MICHELLE M, ROCCA, WALTER A · 2017 to 2017
$4.0M
Multiple Chronic Conditions and AgingR01AG052425 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2017 to 2021
$3.3M
Harnessing the Electronic Health Record to Predict Risk of Cardiovascular DiseaseR01HL136659 · NHLBI · MAYO CLINIC ROCHESTER · PI BIELINSKI, SUZETTE JANINE · 2018 to 2021
$3.2M
Interdisciplinary Infrastructure for Aging Research: Rochester Epidemiology ProjectR33AG058738 · NIA · MAYO CLINIC ROCHESTER · PI LEBRASSEUR, NATHAN K, OLSON, JANET E · 2020 to 2022
$2.4M
NCATS NIH HHS U01 TR002062NCI NIH HHS P30 CA015083NHLBI NIH HHS R01 HL136659NIA NIH HHS R01 AG034676NIA NIH HHS R01 AG052425NIA NIH HHS R33 AG058738NIA NIH HHS RF1 AG055151NIA NIH HHS U54 AG044170NLM NIH HHS R01 LM011934
6 · The paper itself

Abstract

backgroundElectronic health records (EHRs) are a rich source of longitudinal patient data. However, missing information due to clinical care that predated the implementation of EHR system(s) or care that occurred at different medical institutions impedes complete ascertainment of a patient's medical history.

objectiveThis study aimed to investigate information discrepancies and to quantify information gaps by comparing the gynecological surgical history extracted from an EHR of a single institution by using natural language processing (NLP) techniques with the manually curated surgical history information through chart review of records from multiple independent regional health care institutions.

methodsTo facilitate high-throughput evaluation, we developed a rule-based NLP algorithm to detect gynecological surgery history from the unstructured narrative of the Mayo Clinic EHR. These results were compared to a gold standard cohort of 3870 women with gynecological surgery status adjudicated using the Rochester Epidemiology Project medical records-linkage system. We quantified and characterized the information gaps observed that led to misclassification of the surgical status.

resultsThe NLP algorithm achieved precision of 0.85, recall of 0.82, and F1-score of 0.83 in the test set (n=265) relative to outcomes abstracted from the Mayo EHR. This performance attenuated when directly compared to the gold standard (precision 0.79, recall 0.76, and F1-score 0.76), with the majority of misclassifications being false negatives in nature. We then applied the algorithm to the remaining patients (n=3340) and identified 2 types of information gaps through error analysis. First, 6% (199/3340) of women in this study had no recorded surgery information or partial information in the EHR. Second, 4.3% (144/3340) of women had inconsistent or inaccurate information within the clinical narrative owing to misinterpreted information, erroneous "copy and paste," or incorrect information provided by patients. Additionally, the NLP algorithm misclassified the surgery status of 3.6% (121/3340) of women.

conclusionsAlthough NLP techniques were able to adequately recreate the gynecologic surgical status from the clinical narrative, missing or inaccurately reported and recorded information resulted in much of the misclassification observed. Therefore, alternative approaches to collect or curate surgical history are needed.

Indexed as

Electronic Health RecordsNatural Language ProcessingAlgorithmsCohort StudiesFemaleGynecologic Surgical ProceduresHumansdigital healtheHealthelectronic health recordsgynecologic surgerygynecologyhealth information interoperabilityinformation gapmedical informaticsnatural language processingsurgery

Identifiers

PMID35089141
PMCPMC8838563

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.