Evidence map›Paper›PMID 35089067›Full record

ArticlemBio2022

PixR, a Novel Activator of Conjugative Transfer of IncX4 Resistance Plasmids, Mitigates the Fitness Cost of

Lingxian Yi, Romain Durand, Frédéric Grenier, Jun Yang, Kaiyang Yu, Vincent Burrus, Jian-Hua Liu

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Antibiotic and colistin resistance pattern ofNew microbes and new infections · 2025
    Article
  5. Chronic Heat Stress Can Induce Conjugation of a NovelAntibiotics (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Case Report: Transferable IncX4 plasmid carryingFrontiers in veterinary science · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Mobile Colistin Resistance (Antibiotics (Basel, Switzerland) · 2023
    Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Lingxian Yi *College of Veterinary Medicine, National Risk Assessment Laboratory for Antimicrobial Resistance of Microorganisms in Animals, Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural University, Guangzhou, China.
Romain Durand *Département de biologie, Université de Sherbrookegrid.86715.3d, Sherbrooke, Québec, Canada.ORCID 0000-0002-7681-4727
Frédéric GrenierDépartement de biologie, Université de Sherbrookegrid.86715.3d, Sherbrooke, Québec, Canada.
Jun YangCollege of Veterinary Medicine, National Risk Assessment Laboratory for Antimicrobial Resistance of Microorganisms in Animals, Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural University, Guangzhou, China.
Kaiyang YuCollege of Veterinary Medicine, National Risk Assessment Laboratory for Antimicrobial Resistance of Microorganisms in Animals, Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural University, Guangzhou, China.
Vincent BurrusDépartement de biologie, Université de Sherbrookegrid.86715.3d, Sherbrooke, Québec, Canada.ORCID 0000-0001-6318-6904
Jian-Hua LiuCollege of Veterinary Medicine, National Risk Assessment Laboratory for Antimicrobial Resistance of Microorganisms in Animals, Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural University, Guangzhou, China.ORCID 0000-0002-3930-7857
South China Agricultural University · CNUniversité de Sherbrooke · CA

Funding

CIHR PJT-153071
6 · The paper itself

Abstract

The emergence of the plasmid-borne colistin resistance gene

Indexed as

Escherichia coliEscherichia coli ProteinsAnti-Bacterial AgentsColistinDrug Resistance, BacterialMicrobial Sensitivity TestsPlasmidsAnti-Bacterial AgentsColistinEscherichia coli ProteinsMCR-1 protein, E coliconjugationfitnessIncX4mcr-1plasmids

Identifiers

PMID35089067
PMCPMC8725589
OpenAlexW4220692116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.