Evidence map›Paper›PMID 35088608›Full record

ArticleInternational journal of immunopathology and pharmacology

Protective effect of baicalin against arsenic trioxide-induced acute hepatic injury in mice through JAK2/STAT3 signaling pathway.

Qianqian He, Xiaoqi Sun, Muqing Zhang, Li Chu, Yang Zhao, Yongchao Wu, Jianping Zhang, Xue Han, Shengjiang Guan, Chao Ding

Open access · goldAbstract read
In one paragraph

Article in International journal of immunopathology and pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Biomolecules · 2025
    Review
  6. Baicalin plays a protective role by regulating ferroptosis in multiple diseases.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  7. Selenium enrichment enhances the alleviating effect ofCurrent research in food science · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Qianqian HeSchool of Pharmacy, 441322Hebei University of Chinese Medicine, Shijiazhuang, China.
Xiaoqi SunSchool of Pharmacy, 441322Hebei University of Chinese Medicine, Shijiazhuang, China.
Muqing ZhangAffiliated Hospital, 441322Hebei University of Chinese Medicine, Shijiazhuang, China.
Li ChuSchool of Pharmacy, 441322Hebei University of Chinese Medicine, Shijiazhuang, China.ORCID https://orcid.org/0000-0002-6301-2709
Yang Zhao117878The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Yongchao Wu117878The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Jianping ZhangHebei Key Laboratory of Integrative Medicine on Liver-Kidney Patterns, Shijiazhuang, China.
Xue HanSchool of Pharmacy, 441322Hebei University of Chinese Medicine, Shijiazhuang, China.
Shengjiang GuanAffiliated Hospital, 441322Hebei University of Chinese Medicine, Shijiazhuang, China.ORCID https://orcid.org/0000-0003-3743-2870
Chao DingDepartment of Cardiology, Bethune International Peace Hospital of PLA, Shijiazhuang, China.
Hebei University of Chinese Medicine · CNHebei Medical University · CNBethune International Peace Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Baicalin (BA) is a kind of flavonoid that is isolated from

Indexed as

Arsenic TrioxideAnimalsAntioxidantsApoptosisChemical and Drug Induced Liver InjuryFlavonoidsJanus Kinase 2LiverMaleMiceProtective AgentsReactive Oxygen SpeciesSignal TransductionSTAT3 Transcription FactorAntioxidantsArsenic TrioxidebaicalinFlavonoidsJak2 protein, mouseJanus Kinase 2Protective AgentsReactive Oxygen SpeciesStat3 protein, mouseSTAT3 Transcription Factoracute hepatic injuryapoptosisarsenic trioxidebaicalinJAK2/STAT3oxidative stress

Identifiers

PMID35088608
PMCPMC8801635
OpenAlexW4210786304

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.