ArticleObesity (Silver Spring, Md.)2022
Metabolic adaptation delays time to reach weight loss goals.
Article in Obesity (Silver Spring, Md.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Obesity in South and Southeast Asia-A new consensus on care and management.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023Guideline
- Trial
- Adaptive Thermogenesis After Hypocaloric Low-Carbohydrate Versus Low-Fat Diets in African American Women: A Secondary Analysis.Obesity (Silver Spring, Md.) · 2025Trial
- Adaptive thermogenesis, at the level of resting energy expenditure, after diet alone or diet plus bariatric surgery.Obesity (Silver Spring, Md.) · 2024Trial
- Trial
- International Society of Sports Nutrition position stand: diets for body weight reduction.Journal of the International Society of Sports Nutrition · 2026Review
- Long-term management of body weight and physiological mechanisms of weight regain.Journal of molecular cell biology · 2026Review
- Review
- Adherence to Behavioral Weight Management: A Scoping Review of Definitions, Measurement, and Components.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Article
- Post-operative Metabolic Adaptation and its Influence on Long-Term Recurrent Weight Gain After Metabolic and Bariatric Surgery.Obesity surgery · 2026Article
- Dietary and Behavioral Strategies for Weight Loss and Weight Loss Maintenance: A Narrative Review.Nutrients · 2025Review
- Changes in Trunk, but Not Limb, Lean Body Mass Contribute to Variability in Metabolic Adaptation Following Weight Loss.Obesity science & practice · 2025Article
- Metabolic adaptation following gastric bypass surgery: results from a 2-year observational study.International journal of obesity (2005) · 2024Observational
- Metabolic liability for weight gain in early adulthood.Cell reports. Medicine · 2024Article
- Sex Differences in Early Weight Loss Success During a Diabetes Prevention Intervention.American journal of health behavior · 2023Article
- Thirty Obesity Myths, Misunderstandings, and/or Oversimplifications: An Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) 2022.Obesity pillars · 2022Article
- Metabolic adaptation after combined resistance and aerobic exercise training in older women.Obesity (Silver Spring, Md.) · 2022Article
- Metabolic adaptation is associated with less weight and fat mass loss in response to low-energy diets.Nutrition & metabolism · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
objectiveThe aim of this study was to determine whether metabolic adaptation, at the level of resting metabolic rate, was associated with time to reach weight loss goals, after adjusting for confounders.
methodsA total of 65 premenopausal women with overweight (BMI: 28.6 ± 1.5 kg/m
resultsParticipants lost on average 12.5 ± 3.1 kg (16.1% ± 3.4%) over 155.1 ± 49.2 days. Average dietary adherence was 63.6% ± 31.0%. There was significant metabolic adaptation after weight loss (-46 ± 113 kcal/d, p = 0.002) and this variable was a significant predictor of time to reach weight loss goals (β = -0.1, p = 0.041), even after adjusting for confounders (R
conclusionIn premenopausal women with overweight, metabolic adaptation after a 16% weight loss increases the length of time necessary to achieve weight loss goals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.