Evidence map›Paper›PMID 35088520›Full record

ArticleThoracic cancer2022

Operative outcomes and long-term survival of patients undergoing colon interposition after esophagectomy for cancer.

Tomohiro Akutsu, Takeo Fujita, Daisuke Kajiyama, Asako Ozaki, Kazuma Sato, Hisashi Fujiwara, Takashi Kojima, Hiroyuki Daiko

Open access · goldAbstract read
In one paragraph

Article in Thoracic cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tomohiro AkutsuDivision of Esophageal Surgery, National Cancer Center Hospital East, Chiba, Japan.
Takeo FujitaDivision of Esophageal Surgery, National Cancer Center Hospital East, Chiba, Japan.ORCID 0000-0002-6098-9813
Daisuke KajiyamaDivision of Esophageal Surgery, National Cancer Center Hospital East, Chiba, Japan.
Asako OzakiDivision of Esophageal Surgery, National Cancer Center Hospital East, Chiba, Japan.
Kazuma SatoDivision of Esophageal Surgery, National Cancer Center Hospital East, Chiba, Japan.
Hisashi FujiwaraDivision of Esophageal Surgery, National Cancer Center Hospital East, Chiba, Japan.
Takashi KojimaDivision of Gastrointestinal Oncology, National Cancer Center Hospital East, Chiba, Japan.
Hiroyuki DaikoDivision of Esophageal Surgery, National Cancer Center Hospital, Tokyo, Japan.
National Cancer Center Hospital East · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe first choice of an esophageal substitute after esophagectomy for cancer is the stomach. However, the colon must be considered for reconstruction in specific situations. The purpose of this study was to clarify the frequency and clinical features of patients who underwent colon interposition in thoracic esophagectomy and to investigate the postoperative complications and survival.

methodsWe conducted a retrospective case-control study in the National Cancer Center Hospital East, Japan. Patients who underwent colon interposition after esophagectomy for cancer between 2010 and 2020 were analyzed.

resultsEighty-eight patients underwent esophagectomy with colon interposition; 53.2% received preoperative treatment and 52.3% underwent thoracoscopic surgery. Clavien-Dindo grade >III postoperative complications occurred in 42% of the patients; anastomotic leakage was the most common complication, occurring in 26.1% of the cases. Univariate analysis of the factors associated with Clavien-Dindo grade <III complications showed that the period 2015-2020 and totally mechanical Collard anastomosis were significant factors, with odds ratios (OR) of 0.264 and 0.267 (p = 0.00327 and p = 0.00335), respectively. Totally mechanical Collard anastomosis was associated with a lower risk of anastomotic leakage by univariate and multivariate analysis (OR, 0.257, p = 0.00566 and OR, 0.285, p = 0.133, respectively). Three-year overall survival was 54.2%. Univariate and multivariate analysis of overall survival showed that older age was a risk factor (OR, 1.08) for complications.

conclusionIn colon reconstruction after esophageal cancer resection, totally mechanical Collard anastomosis for cervical anastomosis may reduce the risk of Clavien-Dindo grade >III complications.

Indexed as

Esophageal NeoplasmsEsophagectomyAnastomotic LeakCase-Control StudiesColonHumansPostoperative ComplicationsRetrospective Studiesanastomotic leakcancercolonesophagectomysurgical anastomosis

Identifiers

PMID35088520
PMCPMC8930463
OpenAlexW4210317432

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.