ArticleDigestive diseases and sciences2022
Identifying Ascites in Patients with Cirrhosis Using Administrative Codes and Diuretic Use: A Multicenter Study.
Article in Digestive diseases and sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Development and evaluation of a hybrid algorithm for identifying hospitalized patients with cirrhosis.Canadian liver journal · 2026Article
- Impact of Ascites on Morbidity and Length of Hospital Stay: A Large Retrospective Study from a Tertiary Referral Center.Medicina (Kaunas, Lithuania) · 2026Article
- Safety and effectiveness of phenobarbital vs. benzodiazepines for severe alcohol withdrawal in alcohol-associated liver disease in the ICU.JHEP reports : innovation in hepatology · 2026Article
- Comparing the cost of cirrhosis to other common chronic diseases: A longitudinal study in a large national insurance database.Hepatology (Baltimore, Md.) · 2025Article
- High Hospitalization Rates and Risk Factors Among Frail Patients With Cirrhosis: A 10-year Population-based Cohort Study.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2025Article
- Accurate Identification of Patients with Cirrhosis and Its Complications in the Electronic Health Record.Digestive diseases and sciences · 2023Review
- Incidence of, Risk Factors for, and Outcomes After Ascites in a Population-Based Cohort of Older Americans.Digestive diseases and sciences · 2022Article
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Authors and funding
4 authors.
Funding
Abstract
backgroundAscites is associated with significantly increased morbidity, mortality, and health care costs. Large population studies are necessary to determine the burden and impact of ascites; however, ascites ICD-10 codes perform poorly in the identification of patients.
methodsWe utilized three independent retrospective cohorts at the University of Michigan (cohorts 1 and 2) and Duke University (cohort 3). Cohort 1: Child A5-6 patients followed up to 10 years (n = 150); cohort 2: Child A5-B7 patients with portal hypertension followed for up to 1 year (n = 65); cohort 3: cross-sectional cohort of patients evaluated for liver transplant (n = 100). We computed performance characteristics for ascites-related ICD-10 codes (K70.31, K70.11, K71.51, R18.8), as well as loop and/or potassium-sparing diuretics.
resultsA total of 315 patients were included across three cohorts. Algorithms including any ascites code provided better sensitivity and equivalent specificity to R18.8 alone for all cohorts. In cohort 2, we found that loop diuretics, potassium-sparing diuretics, and a combination of both with a cirrhosis code were highly sensitive (82.3% for each) and specific (89.1-93.5%). In contrast, ascites codes were insensitive. In patients with moderate-severe ascites, a combination of recorded diuretics showed high sensitivity and specificity (95.2% and 86.8%). In Cohort 3's transplant evaluation patients, we found that loop diuretics, potassium-sparing diuretics, and a combination of both with a cirrhosis code were highly sensitive (90.4%, 78.8% and 75.0%, respectively) and specific (85.0%, 90.0% and 95.0%, respectively). For moderate-severe cirrhosis, loop diuretics and R18.8 showed higher sensitivity (77.8%) and specificity (88.9%), respectively.
conclusionDiuretic records with a cirrhosis code improve the identification of ascites. This method for identifying ascites should be used in future large dataset studies.
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