Evidence map›Paper›PMID 35088093›Full record

SynthesisInternational urogynecology journal2022

Does electroacupuncture benefit mixed urinary incontinence? A systematic review and meta-analysis with trial sequential analysis.

Yang Cui, Quan Li, Delong Wang, Rui Bao, Limiao Li, Jiamin Zhu, Jianuo Li, Zhuxin Li, Jiantao Yin, Xinyu Zhou and 2 more

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International urogynecology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yang CuiHeilongjiang University of Chinese Medicine, Harbin, 150040, China.
Quan LiThe First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, 150040, China.
Delong WangThe Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, 150001, China.
Rui BaoThe Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, 150001, China.
Limiao LiHeilongjiang University of Chinese Medicine, Harbin, 150040, China.
Jiamin ZhuHeilongjiang University of Chinese Medicine, Harbin, 150040, China.
Jianuo LiHeilongjiang University of Chinese Medicine, Harbin, 150040, China.
Zhuxin LiThe Affiliated Hospital of Nantong University, Nantong, 226001, China.
Jiantao YinHeilongjiang University of Chinese Medicine, Harbin, 150040, China.
Xinyu ZhouHeilongjiang University of Chinese Medicine, Harbin, 150040, China.
Hongna YinThe Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, 150001, China. 13101581588@163.com.
Zhongren SunHeilongjiang University of Chinese Medicine, Harbin, 150040, China. 893682646@qq.com.ORCID 0000-0001-5207-0439
Heilongjiang University of Chinese Medicine · CNFirst Affiliated Hospital of Heilongjiang University of Chinese Medicine · CNNantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductin and hypothesisMixed urinary incontinence (MUI) comprises a combination of urgency and stress. The efficacy and safety of electroacupuncture (EA) for the treatment of MUI remain unclear.

objectiveTo assess the efficacy and safety of EA in treating MUI.

methodsWe searched PubMed, CENTRAL, Embase, Web of Science, four Chinese databases, clinical research registration platforms, grey literature, and the reference lists of the selected studies. Risk of bias and quality were evaluated using the Revman 5.4 and Jadad scores. Meta-analysis was performed using Stata 15.1 software. Trial sequential analysis (TSA) was used to assess the stability of the results.

resultsEight randomized controlled trials comprising 847 patients were included. The meta-analysis results showed that compared with antimuscarinic drugs plus pelvic floor muscle training, EA resulted in significantly less pad weight on the 1-h pad test and statistically significantly lower severity scores on the International Consultation on Incontinence Questionnaire Short Form. The change in the 72-h incontinence episode frequency difference was not statistically significant, and there was no outcome of overall response rate and quality of life in this meta-analysis. Few adverse events occurred in the EA group. The TSA results suggested that the result of change from baseline in the 1-h pad test was stable and the evidence was conclusive.

conclusionsEA could be a potential treatment option for MUI and is relatively safe. Nevertheless, because of the limitations of this study, our conclusions should be interpreted with caution, and further studies are needed to confirm the comprehensive clinical efficacy and placebo effect of EA.

Indexed as

ElectroacupunctureUrinary IncontinenceUrinary Incontinence, StressFemaleHumansMalePelvic FloorQuality of LifeRandomized Controlled Trials as TopicTreatment OutcomeUrinary Incontinence, UrgeElectroacupunctureMeta-analysisMixed urinary incontinenceSystematic reviewTrial sequential analysis

Identifiers

PMID35088093
PMCPMC9021078
OpenAlexW4210758743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.