Evidence map›Paper›PMID 35087972›Full record

ReviewRomanian journal of ophthalmology

A review of neovascular glaucoma. Etiopathogenesis and treatment.

Lilia Dumbrăveanu, Valeriu Cușnir, Doina Bobescu

Abstract readReview
In one paragraph

Review in Romanian journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Clinical outcomes of the PAUL Glaucoma implant for neovascular glaucoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Review
  18. Coats disease presenting with vitreous hemorrhage and neovascular glaucoma.American journal of ophthalmology case reports · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lilia DumbrăveanuDepartment of Ophthalmology and Optometry, "Nicolae Testemițanu" State University of Medicine and Pharmacy, Chișinău, Republic of Moldova.
Valeriu CușnirDepartment of Ophthalmology and Optometry, "Nicolae Testemițanu" State University of Medicine and Pharmacy, Chișinău, Republic of Moldova.
Doina BobescuDepartment of Ophthalmology and Optometry, "Nicolae Testemițanu" State University of Medicine and Pharmacy, Chișinău, Republic of Moldova.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neovascular glaucoma (NVG) is a type of secondary glaucoma, refractory to treatment, often incurable, with very poor visual prognosis. It is characterized by the appearance of new vessels over the iris and iridocorneal angle and frequently associates the presence of a fibrovascular membrane which limits the aqueous humor outflow from the anterior chamber. The most common causes of NVG are: central retinal vein occlusion, proliferative diabetic retinopathy, and ocular ischemic syndrome. Once the gonioscopy developed as a part of clinical examination, it became possible to visualize the new vessels of the anterior segment of the eye in early stages and to understand the mechanisms of increased intraocular pressure (IOP), including narrowing and closing of the iridocorneal angle. Also, the modern imaging techniques, such as optical coherence tomography angiography and fluorescein angiography became indispensable for the clinician. Thus, an early diagnosis, followed by starting an appropriate therapy: panretinal photocoagulation or administration of anti-VEGF drugs, with or without hypotensive ocular therapy, allows the preservation of visual functions for patient's better quality of life. However, one or more surgeries will often be required, especially in the advanced stages of the disease, which do not respond to drug therapy. Managing the NVG we should aim to: 1) reduce ocular ischemia and treat its underlying cause, 2) reduce elevated IOP, once installed and 3) control the inflammatory process. Anyway, the best treatment is prevention, so we must be very attentive at patients with risk factors for developing the NVG.

Indexed as

Diabetic RetinopathyGlaucoma, NeovascularMacular EdemaAngiogenesis InhibitorsFemaleHumansPlacenta Growth FactorQuality of LifeAngiogenesis InhibitorsPlacenta Growth Factorangiogenesisanti-VEGFglaucoma surgeryneovascular glaucomaocular ischemia

Identifiers

PMID35087972
PMCPMC8764420

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.