Evidence map›Paper›PMID 35087968›Full record

ArticleBioactive materials2022

3D-printed bioactive ceramic scaffolds with biomimetic micro/nano-HAp surfaces mediated cell fate and promoted bone augmentation of the bone-implant interface

Xiao Liu, Yali Miao, Haifeng Liang, Jingjing Diao, Lijing Hao, Zhifeng Shi, Naru Zhao, Yingjun Wang

Open access · goldAbstract read
In one paragraph

Article in Bioactive materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 73 citations in OpenAlex.

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  3. Hydroxyapatite-cellulose composites: properties, fabrication methods, and applications.Journal of materials science. Materials in medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Xiao LiuNational Engineering Research Center for Tissue Restoration and Reconstruction, Guangzhou, China.
Yali MiaoSchool of Materials Science and Engineering, South China University of Technology, Guangzhou, 510641, China.
Haifeng LiangDepartment of Orthopedics, Zhujiang Hospital, Southern Medical University, No. 253 Industrial Avenue, Haizhu, Guangzhou, 510280, People's Republic of China.
Jingjing DiaoNational Engineering Research Center for Tissue Restoration and Reconstruction, Guangzhou, China.
Lijing HaoNational Engineering Research Center for Tissue Restoration and Reconstruction, Guangzhou, China.
Zhifeng ShiNational Engineering Research Center for Tissue Restoration and Reconstruction, Guangzhou, China.
Naru ZhaoNational Engineering Research Center for Tissue Restoration and Reconstruction, Guangzhou, China.
Yingjun WangNational Engineering Research Center for Tissue Restoration and Reconstruction, Guangzhou, China.
National Research Center for Rehabilitation Technical Aids · CNChina Guangzhou Analysis and Testing Center · CNGuangzhou Regenerative Medicine and Health Guangdong Laboratory · CNSouth China University of Technology · CNZhujiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcium phosphate bio-ceramics are osteo-conductive, but it remains a challenge to promote the induction of bone augmentation and capillary formation. The surface micro/nano-topography of materials can be recognized by cells and then the cell fate are mediated. Traditional regulation methods of carving surface structures on bio-ceramics employ mineral reagents and organic additives, which might introduce impurity phases and affect the biological results. In a previous study, a facile and novel method was utilized with ultrapure water as the unique reagent for hydrothermal treatment, and a uniform hydroxyapatite (HAp) surface layer was constructed on composite ceramics (β-TCP/CaSiO

Indexed as

3D printed porous scaffoldBioactive ceramicsBone augmentationCell fate mediationHAp surface layer

Identifiers

PMID35087968
PMCPMC8777208
OpenAlexW3209033661

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.