Evidence map›Paper›PMID 35087964›Full record

ArticleBioactive materials2022

Spatiotemporally controlled, aptamers-mediated growth factor release locally manipulates microvasculature formation within engineered tissues.

Deepti Rana, Ajoy Kandar, Nasim Salehi-Nik, Ilyas Inci, Bart Koopman, Jeroen Rouwkema

Open access · goldAbstract read
In one paragraph

Article in Bioactive materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Bioprinting Technologies and Bioinks for Vascular Model Establishment.International journal of molecular sciences · 2023
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Deepti RanaDepartment of Biomechanical Engineering, Technical Medical Centre, Faculty of Engineering Technology, University of Twente, 7500, AE, Enschede, the Netherlands.
Ajoy KandarDepartment of Biomechanical Engineering, Technical Medical Centre, Faculty of Engineering Technology, University of Twente, 7500, AE, Enschede, the Netherlands.
Nasim Salehi-NikDepartment of Biomechanical Engineering, Technical Medical Centre, Faculty of Engineering Technology, University of Twente, 7500, AE, Enschede, the Netherlands.
Ilyas InciIzmir Democracy University, Vocational School of Health Services, Department of Dentistry Services, Dental Prosthetics Technology, Izmir, 35140, Turkey.
Bart KoopmanDepartment of Biomechanical Engineering, Technical Medical Centre, Faculty of Engineering Technology, University of Twente, 7500, AE, Enschede, the Netherlands.
Jeroen RouwkemaDepartment of Biomechanical Engineering, Technical Medical Centre, Faculty of Engineering Technology, University of Twente, 7500, AE, Enschede, the Netherlands.
University of Twente · NLIzmir University · TR

Funding

European Research Council 724469
6 · The paper itself

Abstract

Spatiotemporally controlled growth factor (GF) delivery is crucial for achieving functional vasculature within engineered tissues. However, conventional GF delivery systems show inability to recapitulate the dynamic and heterogeneous nature of developing tissue's biochemical microenvironment. Herein, an aptamer-based programmable GF delivery platform is described that harnesses dynamic affinity interactions for facilitating spatiotemporal control over vascular endothelial GF (VEGF

Indexed as

AptamersBiomaterialsCo-cultureSpatiotemporal releaseTissue engineeringVascular endothelial growth factorVascularization

Identifiers

PMID35087964
PMCPMC8777207
OpenAlexW3208787080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.