Evidence map›Paper›PMID 35087911›Full record

ArticleBioMed research international2022

Adiponectin Levels Are Associated with White Matter Lesions (WMLs) and Cognitive Impairment.

Hui Quan, Tongya Yu, Yingying Lin, Jie Pan, Bingjie Mao, Xuan Wang, Junchao Xie, Xueyuan Liu, Yanxin Zhao

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Hui QuanShanghai Tenth People's Hospital of Tongji University, Department of Internal Neurology, Middle Yanchang Rd. 301#, Zhabei District, Shanghai, China 200072.ORCID https://orcid.org/0000-0003-2129-6501
Tongya YuShanghai Tenth People's Hospital of Tongji University, Department of Internal Neurology, Middle Yanchang Rd. 301#, Zhabei District, Shanghai, China 200072.ORCID https://orcid.org/0000-0003-4162-2802
Yingying LinShanghai Tenth People's Hospital of Tongji University, Department of Internal Neurology, Middle Yanchang Rd. 301#, Zhabei District, Shanghai, China 200072.
Jie PanShanghai Tenth People's Hospital of Tongji University, Department of Internal Neurology, Middle Yanchang Rd. 301#, Zhabei District, Shanghai, China 200072.
Bingjie MaoShanghai Tenth People's Hospital of Tongji University, Department of Internal Neurology, Middle Yanchang Rd. 301#, Zhabei District, Shanghai, China 200072.
Xuan WangShanghai Tenth People's Hospital of Tongji University, Department of Internal Neurology, Middle Yanchang Rd. 301#, Zhabei District, Shanghai, China 200072.
Junchao XieShanghai Tenth People's Hospital of Tongji University, Department of Internal Neurology, Middle Yanchang Rd. 301#, Zhabei District, Shanghai, China 200072.
Xueyuan LiuShanghai Tenth People's Hospital of Tongji University, Department of Internal Neurology, Middle Yanchang Rd. 301#, Zhabei District, Shanghai, China 200072.
Yanxin ZhaoShanghai Tenth People's Hospital of Tongji University, Department of Internal Neurology, Middle Yanchang Rd. 301#, Zhabei District, Shanghai, China 200072.ORCID https://orcid.org/0000-0002-8982-7551
Tongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

methodIn the present study, 126 patients, 90 cases in the WML group and 36 cases in the control group, were analyzed to explore the relationship between adiponectin and WMLs. All patients underwent an MRI scan to assess whether white matter lesions happened. And the serum levels of adiponectin were detected by ELISA.

resultsIn this study, according to Fazekas criteria, WMLs were divided into different severity groups. With the increase of WML score, the level of adiponectin decreased, and linear correlation analysis shows that adiponectin is negatively correlated with the severity of white matter lesions (

conclusionThe level of adiponectin is independently associated with WMLs and cognitive function, which suggests that adiponectin may be a protective factor for WMLs and cognitive function.

Indexed as

AdiponectinCognitive DysfunctionWhite MatterCognitionHumansMagnetic Resonance ImagingAdiponectinADIPOQ protein, human

Identifiers

PMID35087911
PMCPMC8789410
OpenAlexW4205349561

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.