Evidence map›Paper›PMID 35087908›Full record

ArticleBioMed research international2022

Impact of Physical Activity and Medication Adherence on the Seizure Frequency and Quality of Life of Epileptic Patients: A Population Study in West Texas.

YoonJung Lee, Yeseul Ahn, Luca Cucullo

Abstract read
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

YoonJung LeeDepartment of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX 79106, USA.
Yeseul AhnDepartment of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX 79106, USA.
Luca CuculloDepartment of Foundation Medical Studies, Oakland University William Beaumont School of Medicine, Rochester, MI 48309, USA.ORCID https://orcid.org/0000-0002-2827-7162

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Testing tobacco smoke toxicity at the blood-brain barrierR01DA029121 · NIDA · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI ABBRUSCATO, THOMAS J, CUCULLO, LUCA · 2011 to 2021
$3.6M
Repurposing Metformin to Offset Stroke Risk and Injury in Comorbid Populations of SmokersR01NS117906 · NINDS · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI ABBRUSCATO, THOMAS J, CUCULLO, LUCA · 2020 to 2024
$2.9M
Blood and Brain Based Biomarkers of Injury to Assess the Cerebrovascular Impact of Emerging Alternatives to Classic Cigarette ProductsR01DA049737 · NIDA · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI ABBRUSCATO, THOMAS J, CUCULLO, LUCA · 2019 to 2021
$1.4M
NIAID NIH HHS P30 AI050410NIDA NIH HHS R01 DA029121NIDA NIH HHS R01 DA049737NINDS NIH HHS R01 NS117906
6 · The paper itself

Abstract

Epilepsy is a neurological disease that affects 1-3% of the population. People with epilepsy (PWE) have poor physical and psychological health and a lower quality of life (QOL) than people without epilepsy. Moreover, PWE has more comorbid conditions (obesity, depression) than general populations. Physical activity (PA) has been reported to have various positive physical and psychological effects in PWE. Meanwhile, poor medication adherence is one of the main precipitating factors for seizure triggers. This study assessed the impact of PA and medication adherence on the seizure frequency and QOL for PWE at the Epilepsy Foundation, West Texas (EFWT). Our results indicate that PA is positively associated with the quality of life and negatively associated with the seizure frequency for PWE at EFWT, which suggests that physically active PWE tend to have fewer seizures and better QOL. Medication adherence did not affect the seizure frequency or QOL in our study. Yet, it is still crucial to encourage medication adherence for PWE since nonadherence is a known seizure promoter. Findings from this study highlight the continuous need to utilize available resources and implement programs to promote physical activity and medication adherence for better seizure control and QOL in PWE at EFWT.

Indexed as

EpilepsyQuality of LifeExerciseHumansMedication AdherenceSeizuresTexas

Identifiers

PMID35087908
PMCPMC8789420

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.