ArticleFrontiers in medicine2021
Genetic Predisposition to Low-Density Lipoprotein Cholesterol May Increase Risks of Both Individual and Familial Alzheimer's Disease.
Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The causal association between circulating metabolites and Alzheimer's disease: a systematic review and meta-analysis of Mendelian randomization studies.Metabolomics : Official journal of the Metabolomic Society · 2025Pooled it
- Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.Genome biology · 2022Pooled it
- Review
- Alterations in the brain lipidome of Alzheimer's disease donors with rareBrain communications · 2026Article
- Association of genetic predisposition to dyslipidemia and physical activity with incident dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Polycystic ovary syndrome and risk of pregnancy-induced hypertension, gestational diabetes mellitus, and preeclampsia: a Bayesian Mendelian randomization study.Diabetology & metabolic syndrome · 2025Article
- Article
- Is the Relationship Between Cardiovascular Disease and Alzheimer's Disease Genetic? A Scoping Review.Genes · 2024Article
- Effect of inflammatory factors on myocardial infarction.BMC cardiovascular disorders · 2024Article
- Impact of insomnia upon inflammatory digestive diseases and biomarkers: a two-sample mendelian randomization research on Europeans.BMC gastroenterology · 2024Article
- A Brief History of the Progress in Our Understanding of Genetics and Lifestyle, Especially Diet, in the Risk of Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2024Review
- Exploring the association between COVID-19 and male genital cancer risk in European population: evidence from mendelian randomization analysis.BMC genomic data · 2023Article
- Associations between adiposity, diabetes, lifestyle factors and the risk of gliomas.Frontiers in medicine · 2023Article
- Article
- Genetically Predicted Obesity Causally Increased the Risk of Hypertension Disorders in Pregnancy.Frontiers in cardiovascular medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.