Evidence map›Paper›PMID 35087832›Full record

ReviewFrontiers in cell and developmental biology2021

The Interplay Between Epigenetic Regulation and CD8

Wai Ki Wong, Bohan Yin, Ching Ying Katherine Lam, Yingying Huang, Jiaxiang Yan, Zhiwu Tan, Siu Hong Dexter Wong

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Tumor-driven stabilization of CD8Frontiers in immunology · 2026
    Review
  6. Review
  7. Review
  8. Accelerating CAR-T Cell Therapies with Small-Molecule Inhibitors.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2025
    Review
  9. Review
  10. Review
  11. Review
  12. Widespread genomicEpigenetics · 2024
    Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Wai Ki WongDepartment of Bioengineering, Imperial College London, London, United Kingdom.
Bohan YinDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.
Ching Ying Katherine LamDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.
Yingying HuangDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.
Jiaxiang YanDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.
Zhiwu TanAIDS Institute and Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, China.
Siu Hong Dexter WongDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.
Hong Kong Polytechnic University · HKImperial College London · GBUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Effective immunotherapy treats cancers by eradicating tumourigenic cells by activated tumour antigen-specific and bystander CD8

Indexed as

adoptive immunotherapyepigenetic regulationT-cell activationT-cell differentiationT-cell exhaustion

Identifiers

PMID35087832
PMCPMC8787221
OpenAlexW4206700306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.