ArticleOcular oncology and pathology2021
Small Choroidal Melanoma: Correlation between Clinical Characteristics and Metastatic Potential.
Article in Ocular oncology and pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors at 1 institution in 1 country.
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Abstract
importanceDiagnosis of small choroidal melanoma is based upon clinical features and presence of factors predictive of local malignant growth. Prognostic biopsy quantifies risk of metastasis.
objectiveThe aim of this study is to explore relationship between clinical characteristics and metastatic potential of a small choroidal melanoma.
designRetrospective review of 53 patients with small choroidal melanoma treated in a tertiary oncology clinic. Patients were derived from 3 cohorts, with pathologic confirmation, with growth confirmation, and those treated only on clinical basis. Based upon prognostic biopsy outcomes, each case was classified into low or high metastatic potential groups. Distribution of clinical characteristics such as age, laterality, symptoms, tumor dimensions, tumor distance from optic nerve and fovea, presence of surface orange pigment, drusen, retinal pigment epithelial atrophy, and subretinal fluid was analyzed between metastatic groups.
main outcome measuresDistribution of clinical characteristics between low or high metastatic potential groups was analyzed.
resultsA total of 53 patients [mean age, 61 years (range, 27-81 years); 32 (60%) men and 21 (40%) women] were classified into pathology confirmed group (
conclusionClinical characteristics do not identify metastatic potential of a small choroidal melanoma.
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