Evidence map›Paper›PMID 35087771›Full record

ReviewFrontiers in pediatrics2021

Cerebral Blood Flow Monitoring in High-Risk Fetal and Neonatal Populations.

Rachel L Leon, Eric B Ortigoza, Noorjahan Ali, Dimitrios Angelis, Joshua S Wolovits, Lina F Chalak

Abstract readReview
In one paragraph

Review in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  3. Article
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  5. Article
  6. Systemic hypotension and patterns of cerebral blood perfusion in newborns.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  7. A Multiscale Mathematical Model for Fetal Gas Transport and Regulatory Systems During Second Half of Pregnancy.International journal for numerical methods in biomedical engineering · 2025
    Article
  8. Review
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rachel L LeonDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Eric B OrtigozaDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Noorjahan AliDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Dimitrios AngelisDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Joshua S WolovitsDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Lina F ChalakDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebrovascular pressure autoregulation promotes stable cerebral blood flow (CBF) across a range of arterial blood pressures. Cerebral autoregulation (CA) is a developmental process that reaches maturity around term gestation and can be monitored prenatally with both Doppler ultrasound and magnetic resonance imaging (MRI) techniques. Postnatally, there are key advantages and limitations to assessing CA with Doppler ultrasound, MRI, and near-infrared spectroscopy. Here we review these CBF monitoring techniques as well as their application to both fetal and neonatal populations at risk of perturbations in CBF. Specifically, we discuss CBF monitoring in fetuses with intrauterine growth restriction, anemia, congenital heart disease, neonates born preterm and those with hypoxic-ischemic encephalopathy. We conclude the review with insights into the future directions in this field with an emphasis on collaborative science and precision medicine approaches.

Indexed as

cerebral autoregulationcerebroplacental Dopplercongenital heart diseasefetal brainfetal MRIhypoxic ischemia encephalopathy (HIE)near-infrared spectroscopyneonatal brain

Identifiers

PMID35087771
PMCPMC8787287

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.