Evidence map›Paper›PMID 35087761›Full record

ArticleFrontiers in oncology2021

A Transfer Learning Radiomics Nomogram for Preoperative Prediction of Borrmann Type IV Gastric Cancer From Primary Gastric Lymphoma.

Bao Feng, Liebin Huang, Yu Liu, Yehang Chen, Haoyang Zhou, Tianyou Yu, Huimin Xue, Qinxian Chen, Tao Zhou, Qionglian Kuang and 5 more

Abstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Bao FengDepartment of Radiology, Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen, China.
Liebin HuangDepartment of Radiology, Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen, China.
Yu LiuSchool of Electronic Information and Automation, Guilin University of Aerospace Technology, Guilin, China.
Yehang ChenSchool of Electronic Information and Automation, Guilin University of Aerospace Technology, Guilin, China.
Haoyang ZhouSchool of Electronic Information and Automation, Guilin University of Aerospace Technology, Guilin, China.
Tianyou YuSchool of Automation Science and Engineering, South China University of Technology, Guangzhou, China.
Huimin XueDepartment of Radiology, Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen, China.
Qinxian ChenDepartment of Radiology, Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen, China.
Tao ZhouDepartment of Radiology, Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen, China.
Qionglian KuangDepartment of Radiology, Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen, China.
Zhiqi YangDepartment of Radiology, Meizhou People's Hospital, Meizhou, China.
Xiangguang ChenDepartment of Radiology, Meizhou People's Hospital, Meizhou, China.
Xiaofeng ChenDepartment of Radiology, Meizhou People's Hospital, Meizhou, China.
Zhenpeng PengDepartment of Radiology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Wansheng LongDepartment of Radiology, Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to differentiate preoperative Borrmann type IV gastric cancer (GC) from primary gastric lymphoma (PGL) by transfer learning radiomics nomogram (TLRN) with whole slide images of GC as source domain data. MATERIALS AND

methodsThis study retrospectively enrolled 438 patients with histopathologic diagnoses of Borrmann type IV GC and PGL. They received CT examinations from three hospitals. Quantitative transfer learning features were extracted by the proposed transfer learning radiopathomic network and used to construct transfer learning radiomics signatures (TLRS). A TLRN, which integrates TLRS, clinical factors, and CT subjective findings, was developed by multivariate logistic regression. The diagnostic TLRN performance was assessed by clinical usefulness in the independent validation set.

resultsThe TLRN was built by TLRS and a high enhanced serosa sign, which showed good agreement by the calibration curve. The TLRN performance was superior to the clinical model and TLRS. Its areas under the curve (AUC) were 0.958 (95% confidence interval [CI], 0.883-0.991), 0.867 (95% CI, 0.794-0.922), and 0.921 (95% CI, 0.860-0.960) in the internal and two external validation cohorts, respectively. Decision curve analysis (DCA) showed that the TLRN was better than any other model. TLRN has potential generalization ability, as shown in the stratification analysis.

conclusionsThe proposed TLRN based on gastric WSIs may help preoperatively differentiate PGL from Borrmann type IV GC.Borrmann type IV gastric cancer, primary gastric lymphoma, transfer learning, whole slide image, deep learning.

Indexed as

Borrmann type IV gastric cancerdeep learningprimary gastric lymphomatransfer learningwhole slide image

Identifiers

PMID35087761
PMCPMC8789309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.