Evidence map›Paper›PMID 35087749›Full record

ArticleFrontiers in oncology2021

Efficacy and Safety of Albumin-Bound Paclitaxel Compared to Docetaxel as Neoadjuvant Chemotherapy for HER2-Negative Breast Cancer.

Zhi-Dong Lv, Hong-Ming Song, Zhao-He Niu, Gang Nie, Shuai Zheng, Ying-Ying Xu, Wei Gong, Hai-Bo Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Zhi-Dong LvBreast Center, The Affiliated Hospital of Qingdao University, Qingdao, China.
Hong-Ming SongBreast Center, The Affiliated Hospital of Qingdao University, Qingdao, China.
Zhao-He NiuBreast Center, The Affiliated Hospital of Qingdao University, Qingdao, China.
Gang NieBreast Center, The Affiliated Hospital of Qingdao University, Qingdao, China.
Shuai ZhengDepartment of Breast and Thyroid Surgery, Heze Municipal Hospital, Heze, China.
Ying-Ying XuDepartment of Breast Surgery, The First Affiliated Hospital of China Medical University, Shenyang, China.
Wei GongDepartment of Thyroid and Breast Surgery, The Second People's Hospital of Kunshan, Kunshan, China.
Hai-Bo WangBreast Center, The Affiliated Hospital of Qingdao University, Qingdao, China.
Affiliated Hospital of Qingdao University · CNChina Medical University · CNFirst People's Hospital of Kunshan · CNHeze Municipal Hospital · CNQingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNanoparticle albumin-bound paclitaxel (nab-paclitaxel) as neoadjuvant chemotherapy (NAC) for breast cancer remains controversial. We conducted a retrospective study to compare the efficacy and safety of nab-paclitaxel with those of docetaxel as neoadjuvant regimens for HER2-negative breast cancer.

methodsIn this retrospective analysis, a total of 159 HER2-negative breast cancer patients who had undergone operation after NAC were consecutively analyzed from May 2016 to April 2018. Patients were classified into the nab-paclitaxel group (n = 79, nab-paclitaxel 260 mg/m

resultsThe pathological complete response (pCR)(ypT0

conclusionsCompared with docetaxel, nab-paclitaxel achieved a higher pCR rate, especially those patients with triple-negative breast cancer or lymph node negative breast cancer. However, there was no significant difference in DFS between the two groups. This study provides a valuable reference for the management of patients with HER2-negative breast cancer.

Indexed as

albumin-bound paclitaxeldocetaxelHer-2-negative breast cancerneoadjuvant chemotherapypathological complete response

Identifiers

PMID35087749
PMCPMC8787090
OpenAlexW4206250006

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.