Evidence map›Paper›PMID 35087724›Full record

ArticleJournal of epilepsy research2021

Therapeutic Challenge in a Case of Recent Onset Refractory Cluster Seizures.

Sachin Sureshbabu, Muralikrishnan Veleri Padmanabhan, Jacob Alappat, Smilu Mohanlal, Sujith Janardhanan, Sellam Karunanidhi, Lakshminarayan Kannan, Dinesh Nayak, Biju Shekhar

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of epilepsy research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sachin SureshbabuDepartment of Neurology, Aster Malabar Institute of Medical Sciences Hospital, Kozhikode, India.
Muralikrishnan Veleri PadmanabhanDepartment of Neurology, Aster Malabar Institute of Medical Sciences Hospital, Kozhikode, India.
Jacob AlappatDepartment of Neurology, Aster Malabar Institute of Medical Sciences Hospital, Kozhikode, India.
Smilu MohanlalDepartment of Neurology, Aster Malabar Institute of Medical Sciences Hospital, Kozhikode, India.
Sujith JanardhananDepartment of Radiology, Aster Malabar Institute of Medical Sciences Hospital, Kozhikode, India.
Sellam KarunanidhiDepartment of Nuclear Medicine, Aster Malabar Institute of Medical Sciences Hospital, Kozhikode, India.
Lakshminarayan KannanDepartment of Neurology, Glaenagles Global Hospital, Chennai, India.
Dinesh NayakDepartment of Neurology, Glaenagles Global Hospital, Chennai, India.
Biju ShekharDepartment of Neuroanaesthesia, Aster Malabar Institute of Medical Sciences Hospital, Kozhikode, India.
Malabar Institute of Medical Sciences · INGlobal Hospitals · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A dilemma exists in context to the timing of surgery in a case presenting with explosive onset seizures secondary to a focal cortical dysplasia (FCD). This case report highlights the challenges faced in the management of a 4-year-old child with recent onset cluster seizures refractory to anti-epileptic drugs. A 4-year-old girl presented with an acute onset of cluster seizures (up to 32 in a day), semiologically characterized by tonic upper limb extension and laughter lasting for few seconds with no response to multiple anti-epileptic drugs. The clinical, electrographic, neuroimaging and interictal positron emission tomography data were concordant and consistent with a left middle frontal gyrus dysplasia which was successfully resected under electrocorticographic guidance. Patient is seizure free at 2 months of follow up. (Engel Class 1). Surgical resection is feasible and potentially more effective in the early phase of clinical presentation of FCD.

Indexed as

Drug resistant epilepsyElectrocorticographyFocal cortical dysplasia

Identifiers

PMID35087724
PMCPMC8767224
OpenAlexW4206293494

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.