ArticleCase reports in orthopedics2022
Continuous Local Antibiotics Perfusion Therapy for Acute Deep Infections after Open Fractures.
Article in Case reports in orthopedics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Continuous local antibiotic perfusion therapy: a prophylactic strategy for Gustilo-Anderson type III open fractures.OTA international : the open access journal of orthopaedic trauma · 2026Article
- Continuous Local Antibiotic Perfusion for Refractory Musculoskeletal Infections: Functional and Patient-reported Outcomes in a 13-Case Series.Journal of orthopaedic case reports · 2026Article
- Treatment of the infected total knee replacement combining DAIR with continuous local antibiotic perfusion: a preliminary case report series.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Article
- Article
- Simultaneous Bilateral Methicillin-Resistant Staphylococcus aureus Infection After Total Knee Arthroplasty Successfully Treated with Continuous Local Antibiotic Perfusion: A Case Report.The American journal of case reports · 2025Article
- Article
- Clinical outcomes of continuous local antibiotic perfusion in combination with debridement antibiotics and implant retention for periprosthetic hip joint infection.Scientific reports · 2025Article
- Prevention and Modern Strategies for Managing Methicillin-Resistant Staphylococcal Infections in Prosthetic Joint Infections (PJIs).Antibiotics (Basel, Switzerland) · 2024Review
- Review
- Effective Management of Methicillin-Resistant Shoulder Septic Arthritis Using Continuous Local Antibiotic Perfusion: A Case Study and Long-Term Follow-Up.The American journal of case reports · 2024Article
- DAIR in treating chronic PJI after total knee arthroplasty using continuous local antibiotic perfusion therapy: a case series study.BMC musculoskeletal disorders · 2024Article
- Novel Local Antifungal Treatment for Fungal Periprosthetic Joint Infection With Continuous Local Antibiotic Perfusion: A Surgical Technique.Arthroplasty today · 2023Article
- Article
- Unraveling the New Perspectives on Antimicrobial Hydrogels: State-of-the-Art and Translational Applications.Gels (Basel, Switzerland) · 2023Review
- Continuous Local Antibiotic Perfusion: A Novel Technique for the Treatment of Orthopaedic Infections: Narrative Review.JB & JS open accessReview
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Unresolved bone and soft tissue infections remain a great hindrance to fracture management worldwide, both economically and functionally for the patient. For this purpose, the benefits of local antibiotic administration besides systemic therapy have been elucidated. We present a retrospective descriptive analysis of six patients (4 males and 2 females) with acute deep infections after open fractures managed using the continuous local antibiotic perfusion (CLAP) therapy. After sufficient debridement, gentamicin solution concentrated at 1,200
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Registered trials
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