ReviewOxidative medicine and cellular longevity2022
Implications of Oxidative Stress in the Pathogenesis and Treatment of Hyperpigmentation Disorders.
Review in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 48 citations in OpenAlex.
- Effects of Snake Fruit-Infused Massage Oil With Traditional Thai Massage on Skin Quality: A Randomized Controlled Trial.TheScientificWorldJournal · 2026Trial
- A Randomized Double-Blind Controlled Evaluation of the Therapeutic Benefits of an Herbal Lip Hydrant.Journal of cosmetic dermatology · 2025Trial
- Skin-Whitening and Anti-Photoaging Activities ofJournal of microbiology and biotechnology · 2026Article
- Seasonal Phytochemical Variation and Bioactivity of Artemisia herba-alba: Comparative Evaluation of Essential Oils and Phenolic Extracts With Antioxidant, Tyrosinase Inhibitory and In Silico Studies.Chemistry & biodiversity · 2026Article
- Persistent Hyperpigmentation Following Coretox Injection: A Review of Adverse Events Associated with Polysorbate 20.Plastic and reconstructive surgery. Global open · 2026Article
- The Protective Potential of Terpenoid-RichJournal of cancer prevention · 2026Article
- Review
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- Transcriptional and Metabolic Networks Underlying Melanin Deposition in Silkie Chicken Muscle: A Multi-Omics Insights.Animals : an open access journal from MDPI · 2026Article
- Identification of Hub genes in melasma using integrated transcriptomic analysis.Bioinformation · 2026Article
- Integrative Machine Learning of Genetic and Lifestyle Factors for Personalized Skin Health.IEEE journal of translational engineering in health and medicine · 2026Article
- 6-Isoprenylindole-3-carboxylic Acid with an Anti-Melanogenic Activity from a Marine-DerivedMarine drugs · 2025Article
- Natural protection against oxidative stress in human skin melanocytes.Communications biology · 2025Review
- Recent Advances in Plant-Based Emulsion Gels: Preparation, Characterization, Applications, and Future Perspectives.Gels (Basel, Switzerland) · 2025Review
- Topically Applied Molecular Hydrogen Normalizes Skin Parameters Associated with Oxidative Stress: A Pilot Study.Antioxidants (Basel, Switzerland) · 2025Article
- Research progress on pathogenesis of skin pigmentation in chronic liver disease.Biomolecules & biomedicine · 2025Review
- Insights on the Anti-Inflammatory and Anti-Melanogenic Effects of 2'-Hydroxy-2,6'-dimethoxychalcone in RAW 264.7 and B16F10 Cells.Current issues in molecular biology · 2025Article
- ROS and calcium signaling are critical determinant of skin pigmentation.Cell calcium · 2025Review
- The Pathogenesis of Oxidative Stress-Induced Chloasma and Its Therapeutic Implications.Clinical, cosmetic and investigational dermatology · 2025Review
- Molecular mechanisms underlying Tao-Hong-Si-Wu decoction treating hyperpigmentation based on network pharmacology, Mendelian randomization analysis, and experimental verification.Pharmaceutical biology · 2024Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxidative stress represents an imbalance between the generation of reactive oxygen and nitrogen species and the ability of antioxidant systems to decompose those products. Oxidative stress is implicated in the pathogenesis of hyperpigmentation, hypopigmentation, melanoma, and other skin diseases. Regulatory networks involving oxidative stress and related pathways are widely represented in hypopigmentation diseases, particularly vitiligo. However, there is no complete review into the role of oxidative stress in the pathogenesis of hyperpigmentation disorders, especially regarding associations involving oxidative stress and cellular signaling pathways. Here, we review oxidative and antioxidant systems, oxidative stress-induced signal transduction mechanisms, and effects of antioxidant drugs used in preclinical and clinical settings in hyperpigmentation disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.