ArticleThe journal of physical chemistry. C, Nanomaterials and interfaces2022
Single-Molecule Force Spectroscopy of a Tetraaryl Succinonitrile Mechanophore.
Article in The journal of physical chemistry. C, Nanomaterials and interfaces, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Modeling Targeted Mechanochemistry in Polymeric Solids.Chemical reviews · 2026Review
- Neighbouring group participation hindered by force as a molecular design for covalent catch bonds.Nature communications · 2026Article
- Turning Stress Into Signal: Mechanochromic Materials in Commodity and Technologically Relevant Polymers.Chemistry, an Asian journal · 2026Review
- Beyond Color Boundaries: Pioneering Developments in Cholesteric Liquid Crystal Photonic Actuators.Micromachines · 2024Review
- Bond breaking of furan-maleimide adductsChemical science · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fluorescent damage reporters that use mechanochemical activation of a covalent bond to elicit an optical signal are emerging tools in material mechanics as a means to access the nanoscale distribution of forces inside materials under stress. A promising class of damage reporters are tetraaryl succinonitriles (TASN), whose mechanical activation results in stable fluorescent radical species. However, in-depth insights into the molecular mechanics of TASN activation are absent, precluding their use as quantitative mechanoprobes. Here we perform single-molecule force spectroscopy experiments to provide these insights. We use a bridged version of the TASN unit, embedded in multi-mechanophore polymer, to enable multiplexed mechanochemical measurements at the single-molecule level. Our experiments reveal that TASN activates at surprisingly low forces and short time scales compared to other covalent mechanophores. These results establish TASN as a promising candidate for reporting the lower end of relevant forces in material mechanics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.