ArticleFrontiers in genetics2021
Causal Association Between Heart Failure and Alzheimer's Disease: A Two-Sample Bidirectional Mendelian Randomization Study.
Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evaluating the Bidirectional Causal Effects of Alzheimer's Disease Across Multiple Conditions: A Systematic Review and Meta-Analysis of Mendelian Randomization Studies.International journal of molecular sciences · 2025Pooled it
- Testing bidirectional associations of major depressive disorder with medical conditions: two-sample Mendelian randomization study.Npj mental health research · 2026Article
- Heart rate response and recovery during exercise and dementia risk: a prospective UK biobank study.Scientific reports · 2025Article
- Causal analysis of 731 immunophenotypes and heart failure: A bidirectional Mendelian randomization study.Medicine · 2025Article
- Protective role of gout against colorectal cancer: a Mendelian randomization study.Discover oncology · 2025Article
- Polygenic risk scores for atrial fibrillation and heart failure and the risk of stroke and dementia.Brain communications · 2025Article
- Associations between maternal gestational diabetes mellitus and offspring cerebral palsy: a two-sample Mendelian randomization study.Translational pediatrics · 2024Article
- Bidirectional Crosstalk between the Heart and Brain in Alzheimer's Disease.Aging and disease · 2024Review
- Causal relationship between the immune phenotype of monocytes and myasthenia gravis: A Mendelian randomization study.Heliyon · 2024Article
- A Mendelian randomization study on the causal effects of cigarette smoking on liver fibrosis and cirrhosis.Frontiers in medicine · 2024Article
- Lipid-lowering drugs affect lung cancer risk via sphingolipid metabolism: a drug-target Mendelian randomization study.Frontiers in genetics · 2023Article
- The pathophysiology of cognitive impairment in individuals with heart failure: a systematic review.Frontiers in cardiovascular medicine · 2023Review
- The Systemic Effects of Exercise on the Systemic Effects of Alzheimer's Disease.Antioxidants (Basel, Switzerland) · 2022Review
- Heart failure and late-onset Alzheimer's disease: A Mendelian randomization study.Frontiers in genetics · 2022Article
- Genetically supported causality between benign prostate hyperplasia and urinary bladder neoplasms: A mendelian randomization study.Frontiers in genetics · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.