Evidence map›Paper›PMID 35087525›Full record

ArticleFrontiers in immunology2021

Pleckstrin Levels Are Increased in Patients with Chronic Periodontitis and Regulated

M Abdul Alim, Duncan Njenda, Anna Lundmark, Marta Kaminska, Leif Jansson, Kaja Eriksson, Anna Kats, Gunnar Johannsen, Catalin Koro Arvidsson, Piotr M Mydel and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

M Abdul AlimDepartment of Dental Medicine, Division of Pediatric Dentistry, Karolinska Institutet, Huddinge, Sweden.
Duncan NjendaDepartment of Dental Medicine, Division of Periodontology, Karolinska Institutet, Huddinge, Sweden.
Anna LundmarkDepartment of Dental Medicine, Division of Pediatric Dentistry, Karolinska Institutet, Huddinge, Sweden.
Marta KaminskaDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland.
Leif JanssonDepartment of Dental Medicine, Division of Periodontology, Karolinska Institutet, Huddinge, Sweden.
Kaja ErikssonDepartment of Dental Medicine, Division of Pediatric Dentistry, Karolinska Institutet, Huddinge, Sweden.
Anna KatsDepartment of Dental Medicine, Division of Periodontology, Karolinska Institutet, Huddinge, Sweden.
Gunnar JohannsenDepartment of Dental Medicine, Division of Periodontology, Karolinska Institutet, Huddinge, Sweden.
Catalin Koro ArvidssonDepartment of Dental Medicine, Division of Periodontology, Karolinska Institutet, Huddinge, Sweden.
Piotr M MydelDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland.
Tülay Yucel-LindbergDepartment of Dental Medicine, Division of Pediatric Dentistry, Karolinska Institutet, Huddinge, Sweden.
Karolinska Institutet · SEEastmaninstitutet · SEJagiellonian University · PLUniversity of Bergen · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic periodontitis (CP) is a bacteria-driven inflammatory disease characterized by the breakdown of gingival tissue, the periodontal ligament, and alveolar bone, leading ultimately to tooth loss. We previously reported the pleckstrin gene (

Indexed as

MAP Kinase Signaling SystemBiomarkersBlood ProteinsChronic PeriodontitisCytokinesFemaleFibroblastsFluorescent Antibody TechniqueGene ExpressionGingivaHumansImmunohistochemistryImmunophenotypingInflammation MediatorsMalePhosphoproteinsBiomarkersBlood ProteinsCytokinesInflammation MediatorsPhosphoproteinsplatelet protein P47chronic periodontitisgingival fibroblastsinflammationMAP kinase pathwaymPGES-1pleckstrinPLEK

Identifiers

PMID35087525
PMCPMC8787058
OpenAlexW4205804397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.