Evidence map›Paper›PMID 35087410›Full record

ReviewFrontiers in pharmacology2021

Investigating the Efficacy and Safety of Thalidomide for Treating Patients With

Yanfei Lu, Zhenbin Wei, Gaohui Yang, Yongrong Lai, Rongrong Liu

2 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06098014 phase1completednot on this mapstarted 2023, after this paper: background citation

Safety & Efficacy of Thalidomide in Children With Transfusion Dependent Thalassemia: a Quasi Randomized Control Trial in a Tertiary Care Hospital in Bangladesh

TypeinterventionalSponsorBangabandhu Sheikh Mujib Medical University, Dhaka, BangladeshRan2023 to 2024Enrolled60ConditionsTransfusion-dependent ThalassemiaArmsThalidomide Capsules, Placebo
NCT07673302 narecruitingnot on this mapstarted 2026, after this paper: background citation

Safety and Efficacy of Hemoglobin F Inducers in Patients With Beta Thalassemia: a Prospective 12 Months Study

TypeinterventionalSponsorRiphah International UniversityRan2026 to 2027Enrolled240ConditionsThalassemiaArmsThalidomide, Hydroxy Urea
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Thalassaemia.Nature reviews. Disease primers · 2026
    Review
  5. A case of SCD controlled by IMiDs and hydroxyurea.International journal of hematology · 2026
    Article
  6. Expression of Immune CheckpointsTurkish journal of haematology : official journal of Turkish Society of Haematology · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. OvercomingActa pharmaceutica Sinica. B · 2022
    Review
  14. Review
  15. Single Nucleotide Polymorphisms inDiagnostics (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yanfei LuDepartment of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Zhenbin WeiDepartment of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Gaohui YangDepartment of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Yongrong LaiDepartment of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Rongrong LiuDepartment of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
First Affiliated Hospital of GuangXi Medical University · CNGuangxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At present, the main therapies for

Indexed as

hemoglobin levelmeta-analysisß-thalassemiathalidomidetherapy

Identifiers

PMID35087410
PMCPMC8786914
OpenAlexW4206317456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.