ArticleFrontiers in behavioral neuroscience2021
The Association Between Loneliness and Inflammation: Findings From an Older Adult Sample.
Article in Frontiers in behavioral neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 54 citations in OpenAlex.
- Social Isolation and Daily Steps Are Associated With Fatigue in Older Women With Cardiovascular Disease: A Secondary Analysis of the MindMoves Trial.Journal of aging and physical activity · 2026Trial
- Article
- Loneliness, Chronic Conditions, and Healthcare Engagement in Japan: A Nationwide Cross-Sectional Study.JMA journal · 2026Article
- Identifying predictor factors for asthma using machine learning: evidence from the English Longitudinal Study of Ageing.BMC public health · 2026Article
- Adapting the Geriatric Medicine 5Ms Framework to Geriatric Dermatology.Drugs & aging · 2026Review
- Social isolation and loneliness associate with early menopause and mortality in women: a UK Biobank cohort study.BMC medicine · 2026Article
- Observational epidemiological studies can mitigate genetic confounding with a genetic relatedness matrix.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Sex-specific associations between loneliness and hair cortisol among older African American adults.Psychoneuroendocrinology · 2026Article
- StepsConnect: A Real-Time Step-Sensing Ambient Display System to Support Connectedness for Family Members Living Apart.Sensors (Basel, Switzerland) · 2026Article
- Experiencing awe in daily life is linked to lower loneliness.Scientific reports · 2026Article
- Escalating loneliness among Chinese American older adults in an affordable housing community: a repeat cross-sectional study (2012-2025).Innovation in aging · 2026Article
- Self-worth systems in aging societies: a narrative review and conceptual framework from self-esteem to healthy longevity.Frontiers in psychology · 2026Review
- Hormonal and Cytokine Imbalances Promote a Proinflammatory Profile in Institutionalized Elderly.Brain sciences · 2025Article
- Does Loneliness Hurt? Effect of Loneliness on Inflammator Biomarkers, Appetite Hormone Regulation, and Cognitive Function Among Typically Developing Adolescents.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2025Article
- Associations of sarcopenia with depression and suicidal ideation: the sex-specific mediating role of loneliness.BMC geriatrics · 2025Article
- Investigating psychosocial factors and systemic inflammation using dried blood spots: a scoping review.Social psychiatry and psychiatric epidemiology · 2025Article
- Psychological stress and social support are associated with opposing single-cell pro-inflammatory gene regulatory mechanisms in adults.bioRxiv : the preprint server for biology · 2025Article
- Vitamin D Deficiency and IL-6: Risk Factors for Preterm Birth in Black Women: A Retrospective Cross-Sectional Study.The Journal of nutrition · 2025Article
- The Psychology of Social Isolation and Loneliness in Later Life.Clinics in geriatric medicine · 2025Review
- Identifying leading anti-inflammatory dietary determinants of depression and loneliness in older adults.Brain, behavior, & immunity - health · 2025Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
Loneliness has been linked to poor mental and physical health outcomes. Past research suggests that inflammation is a potential pathway linking loneliness and health, but little is known about how loneliness assessed in daily life links with inflammation, or about linkages between loneliness and inflammation among older adults specifically. As part of a larger investigation, we examined the cross-sectional associations between loneliness and a panel of both basal and LPS-stimulated inflammatory markers. Participants were 222 socioeconomically and racially diverse older adults (aged 70-90 years; 38% Black; 13% Hispanic) systematically recruited from the Bronx, NY. Loneliness was measured in two ways, with a retrospective trait measure (the UCLA Three Item Loneliness Scale) and an aggregated momentary measure assessed
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.