Evidence map›Paper›PMID 35087101›Full record

ArticleScientific data2022

Histopathological whole slide image dataset for classification of treatment effectiveness to ovarian cancer.

Ching-Wei Wang, Cheng-Chang Chang, Muhammad Adil Khalil, Yi-Jia Lin, Yi-An Liou, Po-Chao Hsu, Yu-Ching Lee, Chih-Hung Wang, Tai-Kuang Chao

Open access · goldAbstract readDataset
In one paragraph

Article in Scientific data, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ching-Wei WangGraduate Institute of Biomedical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan.
Cheng-Chang ChangDepartment of Gynecology and Obstetrics, Tri-Service General Hospital, Taipei, Taiwan.ORCID 0000-0002-7356-446X
Muhammad Adil KhalilGraduate Institute of Biomedical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan.
Yi-Jia LinDepartment of Pathology, Tri-Service General Hospital, Taipei, Taiwan.
Yi-An LiouGraduate Institute of Biomedical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan.
Po-Chao HsuDepartment of Gynecology and Obstetrics, Tri-Service General Hospital, Taipei, Taiwan.
Yu-Ching LeeGraduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, Taipei, Taiwan.
Chih-Hung WangDepartment of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Tai-Kuang ChaoDepartment of Pathology, Tri-Service General Hospital, Taipei, Taiwan. chaotai.kuang@msa.hinet.net.
Tri-Service General Hospital · TWNational Taiwan University of Science and Technology · TW

Funding

Ministry of Science and Technology, Taiwan (Ministry of Science and Technology of Taiwan) MOST109-2221-E-011- 018-MY3
6 · The paper itself

Abstract

Ovarian cancer is the leading cause of gynecologic cancer death among women. Regardless of the development made in the past two decades in the surgery and chemotherapy of ovarian cancer, most of the advanced-stage patients are with recurrent cancer and die. The conventional treatment for ovarian cancer is to remove cancerous tissues using surgery followed by chemotherapy, however, patients with such treatment remain at great risk for tumor recurrence and progressive resistance. Nowadays, new treatment with molecular-targeted agents have become accessible. Bevacizumab as a monotherapy in combination with chemotherapy has been recently approved by FDA for the treatment of epithelial ovarian cancer (EOC). Prediction of therapeutic effects and individualization of therapeutic strategies are critical, but to the authors' best knowledge, there are no effective biomarkers that can be used to predict patient response to bevacizumab treatment for EOC and peritoneal serous papillary carcinoma (PSPC). This dataset helps researchers to explore and develop methods to predict the therapeutic effect of patients with EOC and PSPC to bevacizumab.

Indexed as

Carcinoma, Ovarian EpithelialOvarian NeoplasmsAntineoplastic AgentsBevacizumabFemaleHumansAntineoplastic AgentsBevacizumab

Identifiers

PMID35087101
PMCPMC8795433
OpenAlexW4210395604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.