Observational studyScientific reports2022
Age-related changes in oral sensitivity, taste and smell.
Observational study in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03240965 (Changes in Sensitivity of Swallowing-relevant Structures, Taste and Smell in Stroke Patients), which is not on this map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Changes in Sensitivity of Swallowing-relevant Structures, Taste and Smell in Stroke Patients
Who cites it
24 citing papers in PubMed, 36 citations in OpenAlex.
- Integrating Machine Learning and Expert Sensory Evaluation to Identify Key Drivers of Tomato Fruit Quality: A Multi-Model and Age-Stratified Analysis.Foods (Basel, Switzerland) · 2026Article
- Effects of Oral Health and Functional Characteristics on Taste Sensitivity in Older Adults: Comparative Analysis Using Solution and Taste Strip Tests.Journal of oral rehabilitation · 2026Article
- Ageing of the Oral Mucosa: Mechanisms and Consequences.International dental journal · 2026Review
- Effects of Cognitive Style and Evaluation Context on Hedonic and Sensory Perception of Café Latte: A Comparison of Sensory Booth, Real-Life, and Mixed Reality Environments.Foods (Basel, Switzerland) · 2026Article
- Article
- Assessment and behavioural management options for older adults with declined smell and taste functions: a scoping review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Integrating Sensory Perception and Wearable Monitoring to Promote Healthy Aging: A New Frontier in Nutritional Personalization.Nutrients · 2026Review
- Machine learning elucidates associations between oral microbiota and the decline of sweet taste perception during aging.NPJ science of food · 2026Article
- Prospective Observational Study on Perioperative Dysgeusia and Trace Metal Elements in Patients Undergoing Pancreatoduodenectomy.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2025Article
- Age-related decrease of odorant sensitivity for a selection of nine diverse molecules.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Early detection of Alzheimer's disease using the MEMORIES mnemonic.Chronic diseases and translational medicine · 2025Review
- Insights into salt perception and cognitive impairment among middle-aged and older adults: a scoping review.BMC public health · 2025Article
- Harnessing the fundamental roles of vitamins: the potent anti-oxidants in longevity.Biogerontology · 2025Review
- Evaluation of Taste Perception and Olfactory Function in Adolescents in Relation to the Duration of Type 1 Diabetes.Pediatric diabetes · 2025Article
- Single-cell transcriptomic atlas of taste papilla aging.Aging cell · 2024Article
- Article
- Acoustic Analysis of Swallowing of an Experimental Meal of Three Food Textures: A Comparative Aging Study.Dysphagia · 2024Article
- Establishment of a risk prediction model for olfactory disorders in patients with transnasal pituitary tumors by machine learning.Scientific reports · 2024Article
- Quantitive Assessment of Gustatory Function and Its Association with Demographics, and Systemic Morbidity.Biology · 2024Article
- Barriers and Facilitators of Self-Management in Older People with Type 1 Diabetes: A Narrative Review Focusing on Cognitive Impairment.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Review
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oropharyngeal sensitivity plays a vital role in the initiation of the swallowing reflex and is thought to decline as part of the aging-process. Taste and smell functions appear to decline with age as well. The aim of our study was to generate data of oral sensitivity in healthy participants for future studies and to analyse age-related changes and their interdependence by measuring oral sensitivity, taste, and smell function. The experiment involved 30 participants younger than and 30 participants older than 60. Sensitivity threshold as a surrogate of oral sensitivity was measured at the anterior faucial pillar by electrical stimulation using commercially available pudendal electrode mounted on a gloved finger. Smell and taste were evaluated using commercially available test kits. Mean sensitivity was lower in young participants compared to older participants (1.9 ± 0.59 mA vs. 2.42 ± 1.03 mA; p = 0.021). Young participants also performed better in smell (Score 11.13 ± 0.86 vs 9.3 ± 1.93; p < 0.001) and taste examinations (Score 11.83 ± 1.86 vs 8.53 ± 3.18; p < 0.001). ANCOVA revealed a statistical association between sensitivity and smell (p = 0.08) that was moderated by age (p = 0.044). Electrical threshold testing at the anterior faucial pillar is a simple, safe, and accurate diagnostic measure of oral sensitivity. We detected a decline of oral sensitivity, taste, and smell in older adults.Trial registration: Clinicaltrials.gov, NCT03240965. Registered 7th August 2017- https://clinicaltrials.gov/ct2/show/NCT03240965 .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.