ArticleNature communications2022
Emerging experience-dependent dynamics in primary somatosensory cortex reflect behavioral adaptation.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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Who cites it
21 citing papers in PubMed, 21 citations in OpenAlex.
- Effects of Different Repetitive Transcranial Magnetic Stimulation Targets for Enhancing Motor Learning: A Single-Blind Randomized Controlled Trial.Neural plasticity · 2026Trial
- Brain-wide activity mapping reveals the somatosensory cortex as a sex-specific regulator of hedonic feeding.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Behavioral engagement and stimulus regularities coordinate auditory-prefrontal network activity.PLoS biology · 2026Article
- Experience-dependent development of vagal circuitry in rodents and humans.Neuroscience and biobehavioral reviews · 2026Review
- Article
- Deviance detection via competitive inhibition between local neocortical ensembles.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Somatosensory cortex shapes perceptual decision bias via the superior colliculus.Research square · 2026Article
- Probabilistic Perceptual Decisions during Navigation Are Driven by a Small Subpopulation of Neurons in a Single Cortical Column of the Primary Somatosensory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Sensory adaptation supports flexible evidence accumulation during perceptual decision making.bioRxiv : the preprint server for biology · 2026Article
- An adaptive and flexible role for primary sensory cortex.Nature neuroscience · 2026Review
- Deviance detection via competitive inhibition between local neocortical ensembles.bioRxiv : the preprint server for biology · 2025Article
- Reward history guides focal attention in whisker somatosensory cortex.Nature communications · 2025Article
- Bilateral integration in somatosensory cortex is controlled by behavioral relevance.Nature neuroscience · 2025Article
- Stimulus selection enhances value-modulated somatosensory processing in the superior colliculus.PLoS biology · 2025Article
- The 6-OHDA Parkinson's Disease Mouse Model Shows Deficits in Sensory Behavior.bioRxiv : the preprint server for biology · 2025Article
- Functional diversities within neurons and astrocytes in the adult rat auditory cortex revealed by single-nucleus RNA sequencing.Scientific reports · 2024Article
- Reward history guides focal attention in whisker somatosensory cortex.bioRxiv : the preprint server for biology · 2024Article
- Behavioral strategy shapes activation of the Vip-Sst disinhibitory circuit in visual cortex.Neuron · 2024Article
- A miniaturized mesoscope for the large-scale single-neuron-resolved imaging of neuronal activity in freely behaving mice.Nature biomedical engineering · 2024Article
- Multimodal subspace identification for modeling discrete-continuous spiking and field potential population activity.Journal of neural engineering · 2024Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Behavioral experience and flexibility are crucial for survival in a constantly changing environment. Despite evolutionary pressures to develop adaptive behavioral strategies in a dynamically changing sensory landscape, the underlying neural correlates have not been well explored. Here, we use genetically encoded voltage imaging to measure signals in primary somatosensory cortex (S1) during sensory learning and behavioral adaptation in the mouse. In response to changing stimulus statistics, mice adopt a strategy that modifies their detection behavior in a context dependent manner as to maintain reward expectation. Surprisingly, neuronal activity in S1 shifts from simply representing stimulus properties to transducing signals necessary for adaptive behavior in an experience dependent manner. Our results suggest that neuronal signals in S1 are part of an adaptive framework that facilitates flexible behavior as individuals gain experience, which could be part of a general scheme that dynamically distributes the neural correlates of behavior during learning.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.